Current early diagnostic biomarkers of prostate cancer
Prostate cancer (PCa) has become to have the highest incidence and the second mortality rate in western countries, affecting men's health to a large extent. Although prostate-specific antigen (PSA) was discovered to help diagnose the cancer in an early stage for decades, its specificity is rela...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-08-01
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| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=549;epage=554;aulast=Qu |
| _version_ | 1828258834267766784 |
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| author | Min Qu Shan-Cheng Ren Ying-Hao Sun |
| author_facet | Min Qu Shan-Cheng Ren Ying-Hao Sun |
| author_sort | Min Qu |
| collection | DOAJ |
| description | Prostate cancer (PCa) has become to have the highest incidence and the second mortality rate in western countries, affecting men's health to a large extent. Although prostate-specific antigen (PSA) was discovered to help diagnose the cancer in an early stage for decades, its specificity is relative low, resulting in unnecessary biopsy for healthy people and over-treatment for patients. Thus, it is imperative to identify more and more effective biomarkers for early diagnosis of PCa in order to distinguish patients from healthy populations, which helps guide an early treatment to lower disease-related mortality by noninvasive or minimal invasive approaches. This review generally describes the current early diagnostic biomarkers of PCa in addition to PSA and summarizes the advantages and disadvantages of these biomarkers. |
| first_indexed | 2024-04-13T02:59:21Z |
| format | Article |
| id | doaj.art-0a367adc6a2c43db9fa0c3663040b291 |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-04-13T02:59:21Z |
| publishDate | 2014-08-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-0a367adc6a2c43db9fa0c3663040b2912022-12-22T03:05:30ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622014-08-0116454955410.4103/1008-682X.129211Current early diagnostic biomarkers of prostate cancerMin QuShan-Cheng RenYing-Hao SunProstate cancer (PCa) has become to have the highest incidence and the second mortality rate in western countries, affecting men's health to a large extent. Although prostate-specific antigen (PSA) was discovered to help diagnose the cancer in an early stage for decades, its specificity is relative low, resulting in unnecessary biopsy for healthy people and over-treatment for patients. Thus, it is imperative to identify more and more effective biomarkers for early diagnosis of PCa in order to distinguish patients from healthy populations, which helps guide an early treatment to lower disease-related mortality by noninvasive or minimal invasive approaches. This review generally describes the current early diagnostic biomarkers of PCa in addition to PSA and summarizes the advantages and disadvantages of these biomarkers.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=549;epage=554;aulast=Quearly diagnostic biomarkers; MALAT1-derived miniRNA; PCA3; prostate cancer; PSA |
| spellingShingle | Min Qu Shan-Cheng Ren Ying-Hao Sun Current early diagnostic biomarkers of prostate cancer Asian Journal of Andrology early diagnostic biomarkers; MALAT1-derived miniRNA; PCA3; prostate cancer; PSA |
| title | Current early diagnostic biomarkers of prostate cancer |
| title_full | Current early diagnostic biomarkers of prostate cancer |
| title_fullStr | Current early diagnostic biomarkers of prostate cancer |
| title_full_unstemmed | Current early diagnostic biomarkers of prostate cancer |
| title_short | Current early diagnostic biomarkers of prostate cancer |
| title_sort | current early diagnostic biomarkers of prostate cancer |
| topic | early diagnostic biomarkers; MALAT1-derived miniRNA; PCA3; prostate cancer; PSA |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=549;epage=554;aulast=Qu |
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