Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assa...

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Main Authors: Marta Baczyńska-Strzecha, Jarosław Kalinka
Format: Article
Language:English
Published: Nofer Institute of Occupational Medicine 2017-10-01
Series:International Journal of Occupational Medicine and Environmental Health
Subjects:
Online Access:http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.html
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author Marta Baczyńska-Strzecha
Jarosław Kalinka
author_facet Marta Baczyńska-Strzecha
Jarosław Kalinka
author_sort Marta Baczyńska-Strzecha
collection DOAJ
description Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941
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spelling doaj.art-0a399440cf2845069c19cd916db5d0732022-12-21T20:39:15ZengNofer Institute of Occupational MedicineInternational Journal of Occupational Medicine and Environmental Health1232-10871896-494X2017-10-01306933941Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in PolandMarta Baczyńska-StrzechaJarosław KalinkaObjectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.htmlpregnancyvitamin Dpreterm deliveryvitamin D deficiencypreterm birthpreterm labor
spellingShingle Marta Baczyńska-Strzecha
Jarosław Kalinka
Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
International Journal of Occupational Medicine and Environmental Health
pregnancy
vitamin D
preterm delivery
vitamin D deficiency
preterm birth
preterm labor
title Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
title_full Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
title_fullStr Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
title_full_unstemmed Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
title_short Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
title_sort assessment of correlation between vitamin d level and prevalence of preterm births in the population of pregnant women in poland
topic pregnancy
vitamin D
preterm delivery
vitamin D deficiency
preterm birth
preterm labor
url http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.html
work_keys_str_mv AT martabaczynskastrzecha assessmentofcorrelationbetweenvitamindlevelandprevalenceofpretermbirthsinthepopulationofpregnantwomeninpoland
AT jarosławkalinka assessmentofcorrelationbetweenvitamindlevelandprevalenceofpretermbirthsinthepopulationofpregnantwomeninpoland