Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assa...
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Format: | Article |
Language: | English |
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Nofer Institute of Occupational Medicine
2017-10-01
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Series: | International Journal of Occupational Medicine and Environmental Health |
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Online Access: | http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.html |
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author | Marta Baczyńska-Strzecha Jarosław Kalinka |
author_facet | Marta Baczyńska-Strzecha Jarosław Kalinka |
author_sort | Marta Baczyńska-Strzecha |
collection | DOAJ |
description | Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941 |
first_indexed | 2024-12-19T02:38:31Z |
format | Article |
id | doaj.art-0a399440cf2845069c19cd916db5d073 |
institution | Directory Open Access Journal |
issn | 1232-1087 1896-494X |
language | English |
last_indexed | 2024-12-19T02:38:31Z |
publishDate | 2017-10-01 |
publisher | Nofer Institute of Occupational Medicine |
record_format | Article |
series | International Journal of Occupational Medicine and Environmental Health |
spelling | doaj.art-0a399440cf2845069c19cd916db5d0732022-12-21T20:39:15ZengNofer Institute of Occupational MedicineInternational Journal of Occupational Medicine and Environmental Health1232-10871896-494X2017-10-01306933941Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in PolandMarta Baczyńska-StrzechaJarosław KalinkaObjectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.htmlpregnancyvitamin Dpreterm deliveryvitamin D deficiencypreterm birthpreterm labor |
spellingShingle | Marta Baczyńska-Strzecha Jarosław Kalinka Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland International Journal of Occupational Medicine and Environmental Health pregnancy vitamin D preterm delivery vitamin D deficiency preterm birth preterm labor |
title | Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland |
title_full | Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland |
title_fullStr | Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland |
title_full_unstemmed | Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland |
title_short | Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland |
title_sort | assessment of correlation between vitamin d level and prevalence of preterm births in the population of pregnant women in poland |
topic | pregnancy vitamin D preterm delivery vitamin D deficiency preterm birth preterm labor |
url | http://ijomeh.eu/Assessment-of-correlation-between-vitamin-D-level-and-prevalence-of-preterm-births,68220,0,2.html |
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