ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts

ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts

Despite hundreds of RNA modifications described to date, only RNA editing results in a change in the nucleotide sequence of RNA molecules compared to the genome. In mammals, two kinds of RNA editing have been described so far, adenosine to inosine (A-to-I) and cytidine to uridine (C-to-U) editing. R...

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Bibliographic Details
Main Authors: Riccardo Pecori, Isabel Chillón, Claudio Lo Giudice, Annette Arnold, Sandra Wüst, Marco Binder, Marco Marcia, Ernesto Picardi, Fotini Nina Papavasiliou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ADAR
RNA editing
U-to-C
MultiEditR
DDX58/RIG-I
LINC-P21
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1080626/full

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