Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study

<p>Abstract</p> <p>Background</p> <p>Antihypertensive drug choices and treatment levels are not in accordance with the existing guidelines. We aimed to assess the impact of a guideline implementation intervention on antihypertensive drug prescribing.</p> <p>...

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Main Authors: Helin-Salmivaara Arja, Sipilä Raija, Korhonen Maarit, Ketola Eeva
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Family Practice
Online Access:http://www.biomedcentral.com/1471-2296/12/87
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author Helin-Salmivaara Arja
Sipilä Raija
Korhonen Maarit
Ketola Eeva
author_facet Helin-Salmivaara Arja
Sipilä Raija
Korhonen Maarit
Ketola Eeva
author_sort Helin-Salmivaara Arja
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Antihypertensive drug choices and treatment levels are not in accordance with the existing guidelines. We aimed to assess the impact of a guideline implementation intervention on antihypertensive drug prescribing.</p> <p>Methods</p> <p>In this controlled before and after study, the effects of a multifaceted (education, audit and feedback, local care pathway) quality programme was evaluated. The intervention was carried out in a health centre between 2002 and 2003. From each health care unit (n = 31), a doctor-nurse pair was trained to act as peer facilitators in the intervention.</p> <p>All antihypertensive drugs prescribed by 25 facilitator general practitioners (intervention GPs) and 53 control GPs were retrieved from the nationwide Prescription Register for three-month periods in 2001 and 2003. The proportions of patients receiving specific antihypertensive drugs and multiple antihypertensive drugs were measured before and after the intervention for three subgroups of hypertension patients: hypertension only, with coronary heart disease, and with diabetes.</p> <p>Results</p> <p>In all subgroups, the use of multiple concurrent medications increased. For intervention patients with hypertension only, the odds ratio (OR) was 1.12 (95% CI 0.99, 1.25; p = 0.06) and for controls 1.13 (1.05, 1.21; p = 0.002). We observed no statistically significant differences in the change in the prescribing of specific antihypertensive agents between the intervention and control groups. The use of agents acting on the renin-angiotensin-aldosterone system increased in all subgroups (hypertension only intervention patients OR 1.19 (1.06, 1.34; p = 0.004) and controls OR 1.24 (1.15, 1.34; p < 0.0001).</p> <p>Conclusions</p> <p>A multifaceted guideline implementation intervention does not necessarily lead to significant changes in prescribing performance. Rigorous planning of the interventions and quality projects and their evaluation are essential.</p>
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spelling doaj.art-0a46ce5558c04fd483ba0593971101012022-12-22T01:20:32ZengBMCBMC Family Practice1471-22962011-08-011218710.1186/1471-2296-12-87Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after studyHelin-Salmivaara ArjaSipilä RaijaKorhonen MaaritKetola Eeva<p>Abstract</p> <p>Background</p> <p>Antihypertensive drug choices and treatment levels are not in accordance with the existing guidelines. We aimed to assess the impact of a guideline implementation intervention on antihypertensive drug prescribing.</p> <p>Methods</p> <p>In this controlled before and after study, the effects of a multifaceted (education, audit and feedback, local care pathway) quality programme was evaluated. The intervention was carried out in a health centre between 2002 and 2003. From each health care unit (n = 31), a doctor-nurse pair was trained to act as peer facilitators in the intervention.</p> <p>All antihypertensive drugs prescribed by 25 facilitator general practitioners (intervention GPs) and 53 control GPs were retrieved from the nationwide Prescription Register for three-month periods in 2001 and 2003. The proportions of patients receiving specific antihypertensive drugs and multiple antihypertensive drugs were measured before and after the intervention for three subgroups of hypertension patients: hypertension only, with coronary heart disease, and with diabetes.</p> <p>Results</p> <p>In all subgroups, the use of multiple concurrent medications increased. For intervention patients with hypertension only, the odds ratio (OR) was 1.12 (95% CI 0.99, 1.25; p = 0.06) and for controls 1.13 (1.05, 1.21; p = 0.002). We observed no statistically significant differences in the change in the prescribing of specific antihypertensive agents between the intervention and control groups. The use of agents acting on the renin-angiotensin-aldosterone system increased in all subgroups (hypertension only intervention patients OR 1.19 (1.06, 1.34; p = 0.004) and controls OR 1.24 (1.15, 1.34; p < 0.0001).</p> <p>Conclusions</p> <p>A multifaceted guideline implementation intervention does not necessarily lead to significant changes in prescribing performance. Rigorous planning of the interventions and quality projects and their evaluation are essential.</p>http://www.biomedcentral.com/1471-2296/12/87
spellingShingle Helin-Salmivaara Arja
Sipilä Raija
Korhonen Maarit
Ketola Eeva
Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
BMC Family Practice
title Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
title_full Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
title_fullStr Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
title_full_unstemmed Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
title_short Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
title_sort change in antihypertensive drug prescribing after guideline implementation a controlled before and after study
url http://www.biomedcentral.com/1471-2296/12/87
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AT sipilaraija changeinantihypertensivedrugprescribingafterguidelineimplementationacontrolledbeforeandafterstudy
AT korhonenmaarit changeinantihypertensivedrugprescribingafterguidelineimplementationacontrolledbeforeandafterstudy
AT ketolaeeva changeinantihypertensivedrugprescribingafterguidelineimplementationacontrolledbeforeandafterstudy