Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields

Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields

Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.

Bibliographic Details
Main Authors:	M. Reza Naimi-Jamal, Sara Mashkouri
Format:	Article
Language:	English
Published:	MDPI AG 2009-01-01
Series:	Molecules
Subjects:	Solvent-free reaction Barbituric acid Pyrimidinediones Heterocyclic compounds Ball-milling
Online Access:	http://www.mdpi.com/1420-3049/14/1/474/

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