Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review
Abstract Background Pancreaticopleural fistula (PPF) is a very rare and critical complication of pancreatitis in children. The majority of publications relevant to PPF are case reports. No pooled analyses of PPF cases are available. Little is known about the pathogenesis and optimal therapeutic sche...
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| Format: | Article |
| Language: | English |
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BMC
2020-06-01
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| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12887-020-02174-x |
| _version_ | 1818518161379557376 |
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| author | Jia-yu Zhang Zhao-hui Deng Biao Gong |
| author_facet | Jia-yu Zhang Zhao-hui Deng Biao Gong |
| author_sort | Jia-yu Zhang |
| collection | DOAJ |
| description | Abstract Background Pancreaticopleural fistula (PPF) is a very rare and critical complication of pancreatitis in children. The majority of publications relevant to PPF are case reports. No pooled analyses of PPF cases are available. Little is known about the pathogenesis and optimal therapeutic schedule. The purpose of this study was to identify the pathogenesis and optimal therapeutic schedule of PPF in children. Case presentation The patient was a 13-year-old girl who suffered from intermittent chest tightness and dyspnea for more than 3 months; she was found to have chronic pancreatitis complicated by PPF. The genetic screening revealed SPINK1 mutation. She was treated with endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic retrograde pancreatic drainage (ERPD); her symptoms improved dramatically after the procedures. Conclusions PPF is a rare pancreatic complication in children and causes significant pulmonary symptoms that can be misdiagnosed frequently. PPF in children is mainly associated with chronic pancreatitis (CP); therefore, we highlight the importance of genetic testing. Endoscopic treatment is recommended when conservative treatment is ineffective. |
| first_indexed | 2024-12-11T01:06:16Z |
| format | Article |
| id | doaj.art-0a4b8b4ca75a4045b5868078dcace0b0 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-12-11T01:06:16Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-0a4b8b4ca75a4045b5868078dcace0b02022-12-22T01:26:10ZengBMCBMC Pediatrics1471-24312020-06-012011810.1186/s12887-020-02174-xPancreaticopleural fistula in children with chronic pancreatitis: a case report and literature reviewJia-yu Zhang0Zhao-hui Deng1Biao Gong2Department of Pediatric Digestive Diseases, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of MedicineDepartment of Pediatric Digestive Diseases, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of MedicineDepartment of Digestive Diseases, Shanghai Shuguang Hospital, Shanghai University of Chinese MedicineAbstract Background Pancreaticopleural fistula (PPF) is a very rare and critical complication of pancreatitis in children. The majority of publications relevant to PPF are case reports. No pooled analyses of PPF cases are available. Little is known about the pathogenesis and optimal therapeutic schedule. The purpose of this study was to identify the pathogenesis and optimal therapeutic schedule of PPF in children. Case presentation The patient was a 13-year-old girl who suffered from intermittent chest tightness and dyspnea for more than 3 months; she was found to have chronic pancreatitis complicated by PPF. The genetic screening revealed SPINK1 mutation. She was treated with endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic retrograde pancreatic drainage (ERPD); her symptoms improved dramatically after the procedures. Conclusions PPF is a rare pancreatic complication in children and causes significant pulmonary symptoms that can be misdiagnosed frequently. PPF in children is mainly associated with chronic pancreatitis (CP); therefore, we highlight the importance of genetic testing. Endoscopic treatment is recommended when conservative treatment is ineffective.http://link.springer.com/article/10.1186/s12887-020-02174-xPancreaticopleural fistulaChronic pancreatitisChildCase report |
| spellingShingle | Jia-yu Zhang Zhao-hui Deng Biao Gong Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review BMC Pediatrics Pancreaticopleural fistula Chronic pancreatitis Child Case report |
| title | Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review |
| title_full | Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review |
| title_fullStr | Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review |
| title_full_unstemmed | Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review |
| title_short | Pancreaticopleural fistula in children with chronic pancreatitis: a case report and literature review |
| title_sort | pancreaticopleural fistula in children with chronic pancreatitis a case report and literature review |
| topic | Pancreaticopleural fistula Chronic pancreatitis Child Case report |
| url | http://link.springer.com/article/10.1186/s12887-020-02174-x |
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