Transcriptional Networks Identify BRPF1 as a Potential Drug Target Based on Inflammatory Signature in Primary Lower-Grade Gliomas

Transcriptional Networks Identify BRPF1 as a Potential Drug Target Based on Inflammatory Signature in Primary Lower-Grade Gliomas

Gliomas are the most common tumors of the central nervous system and are classified into grades I-IV based on their histological characteristics. Lower-grade gliomas (LGG) can be divided into grade II diffuse low-grade gliomas and grade III moderate gliomas and have a relatively good prognosis. Howe...

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Bibliographic Details
Main Authors: Mingyang Xia, Huiyao Chen, Tong Chen, Ping Xue, Xinran Dong, Yifeng Lin, Duan Ma, Wenhao Zhou, Wei Shi, Hao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
lower-grade gliomas
inflammatory signature
prognostic marker
drug targets
BRPF1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.766656/full

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