The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report

Neonatal herpes simplex virus infections are rare, normally acquired through vertical transmission in the peripartum period, usually manifesting before 14 days of life and being identified on the basis of history, clinical and laboratory evaluation. We present the case of a small for gestational age...

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Main Authors: Laura Mihaela Suciu, Cristina Oana Marginean
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2022-12-01
Series:Romanian Journal of Infectious Diseases
Subjects:
Online Access:https://rjid.com.ro/articles/2022.4/RJID_2022_4_Art-02.pdf
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author Laura Mihaela Suciu
Cristina Oana Marginean
author_facet Laura Mihaela Suciu
Cristina Oana Marginean
author_sort Laura Mihaela Suciu
collection DOAJ
description Neonatal herpes simplex virus infections are rare, normally acquired through vertical transmission in the peripartum period, usually manifesting before 14 days of life and being identified on the basis of history, clinical and laboratory evaluation. We present the case of a small for gestational age male infant born at 38 weeks gestational age with neonatal herpes simplex virus infection. The diagnosis was delayed because the attention was focused on an unidentified bacterial infection. In cases where a clinical picture suggestive of infection is described, with laboratory tests that support the diagnosis of infection, but with cultures that do not highlight bacterial or mycological agents, we must not forget about viral agents, specifically among those newborns from intrauterine growth restricted pregnancies. Neonatal HSV infections can be present even in the absence of herpetic vesicles in the newborn and even if the mother is asymptomatic.
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spelling doaj.art-0a547e08dc0c43089f56d6a220a8cc402023-08-11T08:30:04ZengAmaltea Medical Publishing HouseRomanian Journal of Infectious Diseases1454-33892069-60512022-12-0125411311610.37897/RJID.2022.4.2The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case reportLaura Mihaela Suciu0Cristina Oana Marginean1Department of Neonatology, Mures Clinical County Hospital, Targu-Mures, Romania; Department of Neonatology, ”George Emil Palade” University of Medicine, Pharmacy, Sciencies and Technology, Targu-Mures, RomaniaDepartment of Pediatrics, Clinical County Emergency Hospital, Targu-Mures, Romania; Department of Pediatrics, ”George Emil Palade” University of Medicine, Pharmacy, Sciencies and Technology, Targu-Mures, RomaniaNeonatal herpes simplex virus infections are rare, normally acquired through vertical transmission in the peripartum period, usually manifesting before 14 days of life and being identified on the basis of history, clinical and laboratory evaluation. We present the case of a small for gestational age male infant born at 38 weeks gestational age with neonatal herpes simplex virus infection. The diagnosis was delayed because the attention was focused on an unidentified bacterial infection. In cases where a clinical picture suggestive of infection is described, with laboratory tests that support the diagnosis of infection, but with cultures that do not highlight bacterial or mycological agents, we must not forget about viral agents, specifically among those newborns from intrauterine growth restricted pregnancies. Neonatal HSV infections can be present even in the absence of herpetic vesicles in the newborn and even if the mother is asymptomatic.https://rjid.com.ro/articles/2022.4/RJID_2022_4_Art-02.pdfherpes simplex virusinfectiontwin newborn
spellingShingle Laura Mihaela Suciu
Cristina Oana Marginean
The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
Romanian Journal of Infectious Diseases
herpes simplex virus
infection
twin newborn
title The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
title_full The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
title_fullStr The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
title_full_unstemmed The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
title_short The management of neonatal herpes simplex virus infection in a small for gestational age neonate - Case report
title_sort management of neonatal herpes simplex virus infection in a small for gestational age neonate case report
topic herpes simplex virus
infection
twin newborn
url https://rjid.com.ro/articles/2022.4/RJID_2022_4_Art-02.pdf
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