Iron Oxide Nanoparticles as Autophagy Intervention Agents Suppress Hepatoma Growth by Enhancing Tumoricidal Autophagy

Iron Oxide Nanoparticles as Autophagy Intervention Agents Suppress Hepatoma Growth by Enhancing Tumoricidal Autophagy

Abstract The combined treatment with nanoparticles and autophagy inhibitors, such as chloroquine (CQ) and hydroxychloroquine (HCQ), is extensively explored for cancer therapy. However, the toxicity of autophagy inhibitors and their unselective for tumoricidal autophagy have seriously hindered the ap...

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Bibliographic Details
Main Authors: Yuexia Xie, Jiana Jiang, Qianyun Tang, Hanbing Zou, Xue Zhao, Hongmei Liu, Ding Ma, Chenlei Cai, Yan Zhou, Xiaojing Chen, Jun Pu, Peifeng Liu
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Advanced Science
Subjects:
hepatoma therapy
iron oxide nanoparticles
iron transport systems
tumoricidal autophagy
Online Access:https://doi.org/10.1002/advs.201903323

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