Use of Enzymatically Converted Cell-Free DNA (cfDNA) Data for Copy Number Variation-Linked Fragmentation Analysis Allows for Early Colorectal Cancer Detection

Use of Enzymatically Converted Cell-Free DNA (cfDNA) Data for Copy Number Variation-Linked Fragmentation Analysis Allows for Early Colorectal Cancer Detection

The use of non-invasive liquid biopsy-based cell-free DNA (cfDNA) analysis is an emerging method of cancer detection and intervention. Different analytical methodologies are used to investigate cfDNA characteristics, resulting in costly and long analysis processes needed for combining different data...

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Bibliographic Details
Main Authors: Iva Černoša, Fernando Trincado-Alonso, Pol Canal-Noguer, Kristi Kruusmaa, Alexandre Perera-Lluna
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
cfDNA
fragmentation
colorectal cancer
early cancer detection
WGEM
liquid biopsy
Online Access:https://www.mdpi.com/1422-0067/25/6/3502

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