Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia

Background: This study explores effects of instrumental music on the hormonal system (as indicated by serum cortisol and adrenocorticotropic hormone), the immune system (as indicated by immunoglobulin A) and sedative drug requirements during surgery (elective total hip joint replacement under spinal...

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Main Authors: Stefan eKoelsch, Julian eFuermetz, Ulrich eSack, Katrin eBauer, Maximilian eHohenadel, Martin eWiegel, Udo eKaisers, Wolfgang eHeinke
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Psychology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyg.2011.00058/full
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author Stefan eKoelsch
Julian eFuermetz
Ulrich eSack
Katrin eBauer
Maximilian eHohenadel
Martin eWiegel
Udo eKaisers
Wolfgang eHeinke
author_facet Stefan eKoelsch
Julian eFuermetz
Ulrich eSack
Katrin eBauer
Maximilian eHohenadel
Martin eWiegel
Udo eKaisers
Wolfgang eHeinke
author_sort Stefan eKoelsch
collection DOAJ
description Background: This study explores effects of instrumental music on the hormonal system (as indicated by serum cortisol and adrenocorticotropic hormone), the immune system (as indicated by immunoglobulin A) and sedative drug requirements during surgery (elective total hip joint replacement under spinal anaesthesia with light sedation). This is the first study investigating this issue with a double-blind design using instrumental music. Methodology / Principal Findings: Patients (n = 40) were randomly assigned either to a music-group (listening to instrumental music), or to a control-group (listening to a non-musical placebo stimulus). Both groups listened to the auditory stimulus about 2 hours before, and during the entire intra-operative period (during the intra-operative light sedation, subjects were able to respond lethargically to verbal commands). Results indicate that, during surgery, patients of the music-group had a lower propofol consumption, and lower cortisol levels, compared to the control-group. Conclusions / Significance: Our data show that listening to music during surgery under regional anaesthesia has effects on cortisol levels (reflecting stress-reducing effects) and reduces sedative requirements to reach light sedation.
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spelling doaj.art-0a593a7ba424411a8315327dbf13893b2022-12-22T01:14:22ZengFrontiers Media S.A.Frontiers in Psychology1664-10782011-04-01210.3389/fpsyg.2011.0005810114Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesiaStefan eKoelsch0Julian eFuermetz1Ulrich eSack2Katrin eBauer3Maximilian eHohenadel4Martin eWiegel5Udo eKaisers6Wolfgang eHeinke7Freie UniversitätUniversität LeipzigUniversität LeipzigUniversität LeipzigUniversität LeipzigUniversität LeipzigUniversität LeipzigUniversität LeipzigBackground: This study explores effects of instrumental music on the hormonal system (as indicated by serum cortisol and adrenocorticotropic hormone), the immune system (as indicated by immunoglobulin A) and sedative drug requirements during surgery (elective total hip joint replacement under spinal anaesthesia with light sedation). This is the first study investigating this issue with a double-blind design using instrumental music. Methodology / Principal Findings: Patients (n = 40) were randomly assigned either to a music-group (listening to instrumental music), or to a control-group (listening to a non-musical placebo stimulus). Both groups listened to the auditory stimulus about 2 hours before, and during the entire intra-operative period (during the intra-operative light sedation, subjects were able to respond lethargically to verbal commands). Results indicate that, during surgery, patients of the music-group had a lower propofol consumption, and lower cortisol levels, compared to the control-group. Conclusions / Significance: Our data show that listening to music during surgery under regional anaesthesia has effects on cortisol levels (reflecting stress-reducing effects) and reduces sedative requirements to reach light sedation.http://journal.frontiersin.org/Journal/10.3389/fpsyg.2011.00058/fullHormonesMusicPropofolcortisolemotionIgA
spellingShingle Stefan eKoelsch
Julian eFuermetz
Ulrich eSack
Katrin eBauer
Maximilian eHohenadel
Martin eWiegel
Udo eKaisers
Wolfgang eHeinke
Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
Frontiers in Psychology
Hormones
Music
Propofol
cortisol
emotion
IgA
title Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
title_full Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
title_fullStr Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
title_full_unstemmed Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
title_short Effects of music listening on Cortisol levels and Propofol consumption during spinal anaesthesia
title_sort effects of music listening on cortisol levels and propofol consumption during spinal anaesthesia
topic Hormones
Music
Propofol
cortisol
emotion
IgA
url http://journal.frontiersin.org/Journal/10.3389/fpsyg.2011.00058/full
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