Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine

Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine

Abstract The report presents robust and high throughput methods, based on liquid chromatography coupled with evaporative light scattering detection (HPLC-ELSD), for the simultaneous determination of major metabolites of ibuprofen (IBU), namely 2-hydroxyibuprofen and carboxyibuprofen (method A) as we...

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Bibliographic Details
Main Authors:	Justyna Piechocka, Natalia Matwiej, Marta Gaweł, Michał Matyjaszczyk, Rafał Głowacki, Grażyna Chwatko
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-47594-8

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