The Roles of T Helper 1, T Helper 17 and Regulatory T Cells in the Pathogenesis of Sarcoidosis

The Roles of T Helper 1, T Helper 17 and Regulatory T Cells in the Pathogenesis of Sarcoidosis

Sarcoidosis is a systemic granulomatous disorder of unidentified etiology, with a heterogeneous clinical presentation. It is characterized by a reduced delayed-type hypersensitivity to tuberculin and common antigens. The balance between Th1, Th17 and Regulatory T(Treg) cells controls T-cell prolifer...

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Bibliographic Details
Main Authors: Esmaeil Mortaz, Fatemeh Rezayat, Davar Amani, Arda Kiani, Johan Garssen, Ian M. Adcock, Aliakbar Velayati
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-08-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Granuloma
Interleukin 17
Sarcoidosis
Th17 cell
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/695

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