Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species

Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species

Changes in intracellular reactive oxygen species (ROS) levels due to remodeling of antioxidant defense can affect the status of biological homeostasis in aging/oxidative stress. Peroxiredoxin 6 (Prdx6), an antioxidant gene downstream target for the Nrf2 pathway, plays a role in regulating ROS homeos...

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Bibliographic Details
Main Authors: Bhavana Chhunchha, Eri Kubo, Dhirendra P. Singh
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
Klf9
Nrf2
Prdx6
oxidative stress
antioxidant
Online Access:https://www.mdpi.com/2073-4409/11/8/1266

Internet

https://www.mdpi.com/2073-4409/11/8/1266

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