A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments
Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic ma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2015-11-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-65848 |
| _version_ | 1797916750715551744 |
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| author | Mustafa Adem Tatlısu Elif İjlal Çekirdekçi Şükrü Akyüz Zekeriya Nurkalem |
| author_facet | Mustafa Adem Tatlısu Elif İjlal Çekirdekçi Şükrü Akyüz Zekeriya Nurkalem |
| author_sort | Mustafa Adem Tatlısu |
| collection | DOAJ |
| description | Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic manifestations. We report a patient presenting to our hospital with Mobitz type II atrioventricular block after drinking herbal tea prepared from oleander leaves. Three hours after admission, a 200-mg empiric dose of digoxin-specific Fab antibody fragments was administered intravenously over 30 minutes. A 12-lead electrocardiogram (ECG) revealed sinus rhythm at the end of infusion. After 72 hours, the patient was discharged without any symptoms. |
| first_indexed | 2024-04-10T13:02:18Z |
| format | Article |
| id | doaj.art-0a6a60e291344ca0a2d8d8182d18254c |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:02:18Z |
| publishDate | 2015-11-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-0a6a60e291344ca0a2d8d8182d18254c2023-02-15T16:13:05ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692015-11-0143764865010.5543/tkda.2015.65848TKDA-65848A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragmentsMustafa Adem Tatlısu0Elif İjlal Çekirdekçi1Şükrü Akyüz2Zekeriya Nurkalem3Department of Cardiology, Sivas Numune State Hospital, Sivas, TurkeyDepartment of Cardiology, Corlu State Hospital, Tekirdağ, TurkeyDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular And Thoracic Surgery Hospital, İstanbul, TurkeyDepartment of Cardiology, Istanbul Medipol University, İstanbul, TurkeyNerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic manifestations. We report a patient presenting to our hospital with Mobitz type II atrioventricular block after drinking herbal tea prepared from oleander leaves. Three hours after admission, a 200-mg empiric dose of digoxin-specific Fab antibody fragments was administered intravenously over 30 minutes. A 12-lead electrocardiogram (ECG) revealed sinus rhythm at the end of infusion. After 72 hours, the patient was discharged without any symptoms.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-65848atrioventricular blocknerium oleanderdigoxin/adverse effects |
| spellingShingle | Mustafa Adem Tatlısu Elif İjlal Çekirdekçi Şükrü Akyüz Zekeriya Nurkalem A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments Türk Kardiyoloji Derneği Arşivi atrioventricular block nerium oleander digoxin/adverse effects |
| title | A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments |
| title_full | A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments |
| title_fullStr | A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments |
| title_full_unstemmed | A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments |
| title_short | A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments |
| title_sort | case of mobitz type ii atrioventricular block due to nerium oleander poisoning successfully managed with digoxin specific fab antibody fragments |
| topic | atrioventricular block nerium oleander digoxin/adverse effects |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-65848 |
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