Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
Abstract Many secretory enzymes acquire essential zinc ions (Zn2+) in the Golgi complex. ERp44, a chaperone operating in the early secretory pathway, also binds Zn2+ to regulate its client binding and release for the control of protein traffic and homeostasis. Notably, three membrane transporter com...
Main Authors: | Yuta Amagai, Momo Yamada, Toshiyuki Kowada, Tomomi Watanabe, Yuyin Du, Rong Liu, Satoshi Naramoto, Satoshi Watanabe, Junko Kyozuka, Tiziana Anelli, Tiziana Tempio, Roberto Sitia, Shin Mizukami, Kenji Inaba |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-38397-6 |
Similar Items
-
Author Correction: Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
by: Yuta Amagai, et al.
Published: (2023-06-01) -
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
by: Han Ba Bui, et al.
Published: (2023-08-01) -
CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells
by: Daniele Pittari, et al.
Published: (2022-10-01) -
Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis
by: Rakhee Bajaj, et al.
Published: (2022-04-01) -
Golgi_DF: Golgi proteins classification with deep forest
by: Wenzheng Bao, et al.
Published: (2023-05-01)