Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic
BackgroundCircadian variations in the timing of the onset of stroke symptoms have been described, showing a morning excess of cardiovascular risk. To date, no differences have been found between stroke subtype and time distribution throughout the day. The present study aims to compare the seasonal a...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1372324/full |
| _version_ | 1797244817865965568 |
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| author | Alex Menéndez Albarracín Adrián Valls Carbó Neus Rabaneda Lombarte Bárbara Yugueros Baena Jaime Carbonell Gisbert Belén Flores-Pina Maria-Clara Larrañaga De Bofarull Marina Martínez Sánchez María Hernández-Pérez Alejandro Bustamante Rangel Laura Dorado Bouix Meritxell Gomis Cortina Mònica Millán Tornè Natalia Pérez de la Ossa |
| author_facet | Alex Menéndez Albarracín Adrián Valls Carbó Neus Rabaneda Lombarte Bárbara Yugueros Baena Jaime Carbonell Gisbert Belén Flores-Pina Maria-Clara Larrañaga De Bofarull Marina Martínez Sánchez María Hernández-Pérez Alejandro Bustamante Rangel Laura Dorado Bouix Meritxell Gomis Cortina Mònica Millán Tornè Natalia Pérez de la Ossa |
| author_sort | Alex Menéndez Albarracín |
| collection | DOAJ |
| description | BackgroundCircadian variations in the timing of the onset of stroke symptoms have been described, showing a morning excess of cardiovascular risk. To date, no differences have been found between stroke subtype and time distribution throughout the day. The present study aims to compare the seasonal and circadian rhythm of symptoms onset in ischemic, hemorrhagic, and stroke mimic patients.MethodsThis study was conducted prospectively at a hospital and involved a cohort of stroke alert patients from 2018 to 2021. Stroke subtypes were classified as ischemic stroke, intracerebral hemorrhage (ICH), transient ischemic attack (TIA), and stroke mimic. Clinical variables were recorded, and each patient was assigned to a 4-h interval of the day according to the time of onset of symptoms; unwitnessed stroke patients were analyzed separately. Seasonal changes in stroke distribution were analyzed at 3-month intervals.ResultsA total of 2,348 patients were included in this analysis (ischemic 67%, ICH 13%, mimic 16%, and TIA 3%). Regardless of stroke subtype, most of the patients were distributed between 08–12 h and 12–16 h. Significant differences were found in the time distribution depending on stroke subtype, with ICH predominating in the 4–8 h period (dawn), most of which were hypertensive, TIA in the 12–16 h period (afternoon), and stroke mimic in the 20 h period (evening). The ischemic stroke was evenly distributed throughout the different periods of the day. There were no differences in the seasonal pattern between different stroke subtypes, with winter being the one that accumulated the most cases.ConclusionThe present study showed different circadian patterns of stroke subtypes, with a predominance of ICH at dawn and stroke mimic in the afternoon. The stroke circadian rhythm resembles previous studies, with a higher incidence in the morning and a second peak in the afternoon. |
| first_indexed | 2024-04-24T19:17:03Z |
| format | Article |
| id | doaj.art-0a718a7bc07246b990aab26feb59d891 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-24T19:17:03Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-0a718a7bc07246b990aab26feb59d8912024-03-26T04:57:47ZengFrontiers Media S.A.Frontiers in Neurology1664-22952024-03-011510.3389/fneur.2024.13723241372324Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimicAlex Menéndez AlbarracínAdrián Valls CarbóNeus Rabaneda LombarteBárbara Yugueros BaenaJaime Carbonell GisbertBelén Flores-PinaMaria-Clara Larrañaga De BofarullMarina Martínez SánchezMaría Hernández-PérezAlejandro Bustamante RangelLaura Dorado BouixMeritxell Gomis CortinaMònica Millán TornèNatalia Pérez de la OssaBackgroundCircadian variations in the timing of the onset of stroke symptoms have been described, showing a morning excess of cardiovascular risk. To date, no differences have been found between stroke subtype and time distribution throughout the day. The present study aims to compare the seasonal and circadian rhythm of symptoms onset in ischemic, hemorrhagic, and stroke mimic patients.MethodsThis study was conducted prospectively at a hospital and involved a cohort of stroke alert patients from 2018 to 2021. Stroke subtypes were classified as ischemic stroke, intracerebral hemorrhage (ICH), transient ischemic attack (TIA), and stroke mimic. Clinical variables were recorded, and each patient was assigned to a 4-h interval of the day according to the time of onset of symptoms; unwitnessed stroke patients were analyzed separately. Seasonal changes in stroke distribution were analyzed at 3-month intervals.ResultsA total of 2,348 patients were included in this analysis (ischemic 67%, ICH 13%, mimic 16%, and TIA 3%). Regardless of stroke subtype, most of the patients were distributed between 08–12 h and 12–16 h. Significant differences were found in the time distribution depending on stroke subtype, with ICH predominating in the 4–8 h period (dawn), most of which were hypertensive, TIA in the 12–16 h period (afternoon), and stroke mimic in the 20 h period (evening). The ischemic stroke was evenly distributed throughout the different periods of the day. There were no differences in the seasonal pattern between different stroke subtypes, with winter being the one that accumulated the most cases.ConclusionThe present study showed different circadian patterns of stroke subtypes, with a predominance of ICH at dawn and stroke mimic in the afternoon. The stroke circadian rhythm resembles previous studies, with a higher incidence in the morning and a second peak in the afternoon.https://www.frontiersin.org/articles/10.3389/fneur.2024.1372324/fullstrokechronobiological rhythmcircadian rhythmstroke codehaemorrhagic stroke |
| spellingShingle | Alex Menéndez Albarracín Adrián Valls Carbó Neus Rabaneda Lombarte Bárbara Yugueros Baena Jaime Carbonell Gisbert Belén Flores-Pina Maria-Clara Larrañaga De Bofarull Marina Martínez Sánchez María Hernández-Pérez Alejandro Bustamante Rangel Laura Dorado Bouix Meritxell Gomis Cortina Mònica Millán Tornè Natalia Pérez de la Ossa Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic Frontiers in Neurology stroke chronobiological rhythm circadian rhythm stroke code haemorrhagic stroke |
| title | Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic |
| title_full | Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic |
| title_fullStr | Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic |
| title_full_unstemmed | Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic |
| title_short | Time of the day and season distribution among stroke code subtypes: differences between ischemic stroke, intracranial hemorrhage, and stroke mimic |
| title_sort | time of the day and season distribution among stroke code subtypes differences between ischemic stroke intracranial hemorrhage and stroke mimic |
| topic | stroke chronobiological rhythm circadian rhythm stroke code haemorrhagic stroke |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1372324/full |
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