Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report

Abstract Hyperkeratosis of the nipples and areolae (HNA) is an uncommon skin disorder with no definite aetiology. We report a case of a 16‐year‐old boy, who presented with bilateral pigmentation and thickening of the nipples and areolae, accompanied with linear brown protrusions on the anterior neck...

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Main Authors: Rui‐Ni Wang, Ping‐Shun Zhang, Xiao‐Fang Zhu
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Skin Health and Disease
Online Access:https://doi.org/10.1002/ski2.344
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author Rui‐Ni Wang
Ping‐Shun Zhang
Xiao‐Fang Zhu
author_facet Rui‐Ni Wang
Ping‐Shun Zhang
Xiao‐Fang Zhu
author_sort Rui‐Ni Wang
collection DOAJ
description Abstract Hyperkeratosis of the nipples and areolae (HNA) is an uncommon skin disorder with no definite aetiology. We report a case of a 16‐year‐old boy, who presented with bilateral pigmentation and thickening of the nipples and areolae, accompanied with linear brown protrusions on the anterior neck and a velvet like appearance with pigmentation on the axillary bilaterlly. Based on clinical and histopathological, and dermatoscopic findings, the diagnosis of bilateral HNA accompanied by linear nevus and acanthosis nigricans was made. The skin lesions were improved by treatment with topical calcipotriol gel.
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spelling doaj.art-0a75c7f771e04c8590ca46507453a1c62024-04-03T10:47:27ZengWileySkin Health and Disease2690-442X2024-04-0142n/an/a10.1002/ski2.344Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case reportRui‐Ni Wang0Ping‐Shun Zhang1Xiao‐Fang Zhu2Department of Dermatology of Dingbian County Hospital Shanxi ChinaDepartment of Dermatology of Dingbian County Hospital Shanxi ChinaDepartment of Dermatology of Clinical Medical college of Yangzhou University Jiangsu ChinaAbstract Hyperkeratosis of the nipples and areolae (HNA) is an uncommon skin disorder with no definite aetiology. We report a case of a 16‐year‐old boy, who presented with bilateral pigmentation and thickening of the nipples and areolae, accompanied with linear brown protrusions on the anterior neck and a velvet like appearance with pigmentation on the axillary bilaterlly. Based on clinical and histopathological, and dermatoscopic findings, the diagnosis of bilateral HNA accompanied by linear nevus and acanthosis nigricans was made. The skin lesions were improved by treatment with topical calcipotriol gel.https://doi.org/10.1002/ski2.344
spellingShingle Rui‐Ni Wang
Ping‐Shun Zhang
Xiao‐Fang Zhu
Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
Skin Health and Disease
title Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
title_full Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
title_fullStr Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
title_full_unstemmed Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
title_short Bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans: A rare case report
title_sort bilateral hyperkeratosis of the nipples and areolae with linear nevus and acanthosis nigricans a rare case report
url https://doi.org/10.1002/ski2.344
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AT pingshunzhang bilateralhyperkeratosisofthenipplesandareolaewithlinearnevusandacanthosisnigricansararecasereport
AT xiaofangzhu bilateralhyperkeratosisofthenipplesandareolaewithlinearnevusandacanthosisnigricansararecasereport