Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips

To shorten the production time for PDMS-moulds by additive manufacturing (AM) several 3D printers have been investigated in comparison to standard micro-milling by producing benchmark structures. These are evaluated regarding their shape accuracy, the transparency of the casted PDMS which is linked...

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Main Authors: Schmidt-Speicher Leona M., Mellert Tobias, Hurtado Rivera Andrea C., Länge Kerstin, Ahrens Ralf, Guber Andreas E.
Format: Article
Language:English
Published: De Gruyter 2021-10-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2021-2065
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author Schmidt-Speicher Leona M.
Mellert Tobias
Hurtado Rivera Andrea C.
Länge Kerstin
Ahrens Ralf
Guber Andreas E.
author_facet Schmidt-Speicher Leona M.
Mellert Tobias
Hurtado Rivera Andrea C.
Länge Kerstin
Ahrens Ralf
Guber Andreas E.
author_sort Schmidt-Speicher Leona M.
collection DOAJ
description To shorten the production time for PDMS-moulds by additive manufacturing (AM) several 3D printers have been investigated in comparison to standard micro-milling by producing benchmark structures. These are evaluated regarding their shape accuracy, the transparency of the casted PDMS which is linked to the surface quality of the mould, and the production time until the moulds are ready to use. Even though the additively manufactured moulds showed significantly better surface quality and shorter production time, the necessary shape accuracy for non-square-structures or structures with < 250 μm edge length could not be achieved due to limiting factors like nozzle diameter, size of the digital micromirror device or spot size of the LCD-panel.
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spelling doaj.art-0a7668134a4a422b8827ce91a41778ff2022-12-22T04:06:51ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042021-10-017225525910.1515/cdbme-2021-2065Rapid Prototyping of Moulds for PDMS-based Microfluidic ChipsSchmidt-Speicher Leona M.0Mellert Tobias1Hurtado Rivera Andrea C.2Länge Kerstin3Ahrens Ralf4Guber Andreas E.5Karlsruhe Institute of Technology (KIT), Institute of Microstructure Technology (IMT), Hermann-von-Helmholtz-Platz 1, 76344Eggenstein-Leopoldshafen, GermanyKIT, IMT, 76344Eggenstein-Leopoldshafen, GermanyKIT, IMT, 76344Eggenstein-Leopoldshafen, GermanyKIT, IMT, 76344Eggenstein-Leopoldshafen, GermanyKIT, IMT, 76344Eggenstein-Leopoldshafen, GermanyKIT, IMT, 76344Eggenstein-Leopoldshafen, GermanyTo shorten the production time for PDMS-moulds by additive manufacturing (AM) several 3D printers have been investigated in comparison to standard micro-milling by producing benchmark structures. These are evaluated regarding their shape accuracy, the transparency of the casted PDMS which is linked to the surface quality of the mould, and the production time until the moulds are ready to use. Even though the additively manufactured moulds showed significantly better surface quality and shorter production time, the necessary shape accuracy for non-square-structures or structures with < 250 μm edge length could not be achieved due to limiting factors like nozzle diameter, size of the digital micromirror device or spot size of the LCD-panel.https://doi.org/10.1515/cdbme-2021-2065rapid prototypingadditive manufacturingmicrofluidic systemslab-on-a-chipplant-on-a-chip
spellingShingle Schmidt-Speicher Leona M.
Mellert Tobias
Hurtado Rivera Andrea C.
Länge Kerstin
Ahrens Ralf
Guber Andreas E.
Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
Current Directions in Biomedical Engineering
rapid prototyping
additive manufacturing
microfluidic systems
lab-on-a-chip
plant-on-a-chip
title Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
title_full Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
title_fullStr Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
title_full_unstemmed Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
title_short Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips
title_sort rapid prototyping of moulds for pdms based microfluidic chips
topic rapid prototyping
additive manufacturing
microfluidic systems
lab-on-a-chip
plant-on-a-chip
url https://doi.org/10.1515/cdbme-2021-2065
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