Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans.

Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans.

Simian varicella virus (SVV), the etiologic agent of naturally occurring varicella in primates, is genetically and antigenically closely related to human varicella zoster virus (VZV). Early attempts to develop a model of VZV pathogenesis and latency in nonhuman primates (NHP) resulted in persistent...

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Bibliographic Details
Main Authors: Ilhem Messaoudi, Alexander Barron, Mary Wellish, Flora Engelmann, Alfred Legasse, Shannon Planer, Don Gilden, Janko Nikolich-Zugich, Ravi Mahalingam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2770849?pdf=render

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