Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling

Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling

Chagas disease, caused by <i>Trypanosoma cruzi</i> (<i>T. cruzi</i>), affects nearly eight million people worldwide. There are currently only limited treatment options, which cause several side effects and have drug resistance. Thus, there is a great need for a novel, improve...

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Bibliographic Details
Main Authors: Alfredo Juárez-Saldivar, Michael Schroeder, Sebastian Salentin, V. Joachim Haupt, Emma Saavedra, Citlali Vázquez, Francisco Reyes-Espinosa, Verónica Herrera-Mayorga, Juan Carlos Villalobos-Rocha, Carlos A. García-Pérez, Nuria E. Campillo, Gildardo Rivera
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
antiprotozoal
chagas disease
FDA-Drugs
molecular docking
protein-ligand interaction profiler
repositioning
Online Access:https://www.mdpi.com/1422-0067/21/12/4270

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