QSAR AND MOLECULAR DOCKING STUDY OF GONADOTROPIN-RELEASING HORMONE RECEPTOR INHIBITORS

QSAR AND MOLECULAR DOCKING STUDY OF GONADOTROPIN-RELEASING HORMONE RECEPTOR INHIBITORS

Background: A case study of activities of pyrimidine-based molecules to the gonadotropin-releasing hormone receptor is used to develop a QSAR model. The chemical dataset collected as CHEMBL1855 were curated in line with published works of Prof. Gramatica. The parameters for QSAR model validation and...

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Bibliographic Details
Main Authors: David Ebuka Arthur, Mahmoud E.S. Soliman, Shola Elijah Adeniji, Oluwaseye Adedirin, Florence Peter
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Scientific African
Subjects:
QSAR
Gonadotrophs
Molecular docking
Insurbia plot
Williams plot
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227622001983

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http://www.sciencedirect.com/science/article/pii/S2468227622001983

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