Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension
The main purpose of this study was to investigate the features of within-visit blood pressure variability (BPV) in patients with arterial hypertension (AH) and to assess the relationship of those features to impaired renal filtration. Material and Methods: The study included 120 patients with AH St...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Medical Research and Development Corporation
2017-06-01
|
| Series: | International Journal of Biomedicine |
| Subjects: | |
| Online Access: | http://ijbm.org/articles/IJBM_7(2)_OA1.pdf |
| _version_ | 1819081718291759104 |
|---|---|
| author | Andrey Y. Kravchenko Anna A. Chernykh Andrey V. Budnevsky Evgeniy S. Ovsyannikov Alexey V. Chernov Anna A. Feskova |
| author_facet | Andrey Y. Kravchenko Anna A. Chernykh Andrey V. Budnevsky Evgeniy S. Ovsyannikov Alexey V. Chernov Anna A. Feskova |
| author_sort | Andrey Y. Kravchenko |
| collection | DOAJ |
| description | The main purpose of this study was to investigate the features of within-visit blood pressure variability (BPV) in patients with arterial hypertension (AH) and to assess the relationship of those features to impaired renal filtration.
Material and Methods: The study included 120 patients with AH Stages I and II (ESH/ESC, 2013): 58(48.3%) men and 62(51.7%) women aged from 22 to 73 years (mean age 58.7±15 years). Average duration of AH was 15.0±6.7 years. BP was measured three times during visit. BP was measured three times at 2-minute intervals during one visit. Within-visit BPV was evaluated by the presence of an absolute difference (AD) between any two readings of three SBP measurements of more than 5mmHg. All patients underwent a comprehensive examination, which included blood and urine tests, kidney ultrasound, assessment of blood levels of creatinine and TnT, and calculation of GFR.
Results: Depending on the response of BP to repeated measurements, three types of BPV were identified. A prognostically unfavorable type of BPV, which is characterized by SBP-AD >5mmHg between the third and first measurements, was identified. Patients of this group had the lowest eGFR value that indicates more pronounced renal damage, and, as a consequence, worse prognosis. Also in these patients, there was an increase in TnT level, which is a predictor of the development of adverse cardiovascular complications. |
| first_indexed | 2024-12-21T20:05:14Z |
| format | Article |
| id | doaj.art-0a832d0a1b8845219e92931136edf083 |
| institution | Directory Open Access Journal |
| issn | 2158-0510 2158-0529 |
| language | English |
| last_indexed | 2024-12-21T20:05:14Z |
| publishDate | 2017-06-01 |
| publisher | International Medical Research and Development Corporation |
| record_format | Article |
| series | International Journal of Biomedicine |
| spelling | doaj.art-0a832d0a1b8845219e92931136edf0832022-12-21T18:51:52ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292017-06-0172919510.21103/Article7(2)_OA1Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial HypertensionAndrey Y. Kravchenko0Anna A. Chernykh1Andrey V. Budnevsky2Evgeniy S. Ovsyannikov3Alexey V. Chernov4Anna A. Feskova5Voronezh State Medical University named after N.N. Burdenko Voronezh State Medical University named after N.N. Burdenko Voronezh State Medical University named after N.N. Burdenko Voronezh State Medical University named after N.N. Burdenko Voronezh State Medical University named after N.N. Burdenko Voronezh State Medical University named after N.N. Burdenko The main purpose of this study was to investigate the features of within-visit blood pressure variability (BPV) in patients with arterial hypertension (AH) and to assess the relationship of those features to impaired renal filtration. Material and Methods: The study included 120 patients with AH Stages I and II (ESH/ESC, 2013): 58(48.3%) men and 62(51.7%) women aged from 22 to 73 years (mean age 58.7±15 years). Average duration of AH was 15.0±6.7 years. BP was measured three times during visit. BP was measured three times at 2-minute intervals during one visit. Within-visit BPV was evaluated by the presence of an absolute difference (AD) between any two readings of three SBP measurements of more than 5mmHg. All patients underwent a comprehensive examination, which included blood and urine tests, kidney ultrasound, assessment of blood levels of creatinine and TnT, and calculation of GFR. Results: Depending on the response of BP to repeated measurements, three types of BPV were identified. A prognostically unfavorable type of BPV, which is characterized by SBP-AD >5mmHg between the third and first measurements, was identified. Patients of this group had the lowest eGFR value that indicates more pronounced renal damage, and, as a consequence, worse prognosis. Also in these patients, there was an increase in TnT level, which is a predictor of the development of adverse cardiovascular complications.http://ijbm.org/articles/IJBM_7(2)_OA1.pdfarterial hypertensionblood pressure variabilityglomerular filtration ratechronic kidney disease |
| spellingShingle | Andrey Y. Kravchenko Anna A. Chernykh Andrey V. Budnevsky Evgeniy S. Ovsyannikov Alexey V. Chernov Anna A. Feskova Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension International Journal of Biomedicine arterial hypertension blood pressure variability glomerular filtration rate chronic kidney disease |
| title | Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension |
| title_full | Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension |
| title_fullStr | Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension |
| title_full_unstemmed | Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension |
| title_short | Relationship Between Within-Visit Blood Pressure Variability and Kidney Function in Patients with Arterial Hypertension |
| title_sort | relationship between within visit blood pressure variability and kidney function in patients with arterial hypertension |
| topic | arterial hypertension blood pressure variability glomerular filtration rate chronic kidney disease |
| url | http://ijbm.org/articles/IJBM_7(2)_OA1.pdf |
| work_keys_str_mv | AT andreyykravchenko relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension AT annaachernykh relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension AT andreyvbudnevsky relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension AT evgeniysovsyannikov relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension AT alexeyvchernov relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension AT annaafeskova relationshipbetweenwithinvisitbloodpressurevariabilityandkidneyfunctioninpatientswitharterialhypertension |