Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis
Abstract Autoimmune hemolytic anemia (AIHA) is a rare disease with a rate of 1-3 in 100,000 in adults. AIHA are defined as primary (idiopathic) or secondary depending on the presence or absence of accompanying disease. Secondary causes include drugs, immunodeficiencies, infections, other autoimmune...
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| Format: | Article |
| Language: | English |
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Nizameddin KOCA
2021-03-01
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| Series: | Turkish Journal of Internal Medicine |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1565392 |
| _version_ | 1797916199550451712 |
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| author | Mehmet Sezen Abdülmecit Yıldız Mahmut Yavuz Kamil Dilek Mustafa Güllülü Ayşegül Oruç Mehmet Fethullah Aydın Alparslan Ersoy |
| author_facet | Mehmet Sezen Abdülmecit Yıldız Mahmut Yavuz Kamil Dilek Mustafa Güllülü Ayşegül Oruç Mehmet Fethullah Aydın Alparslan Ersoy |
| author_sort | Mehmet Sezen |
| collection | DOAJ |
| description | Abstract
Autoimmune hemolytic anemia (AIHA) is a rare disease with a rate of 1-3 in 100,000 in adults. AIHA are defined as primary (idiopathic) or secondary depending on the presence or absence of accompanying disease. Secondary causes include drugs, immunodeficiencies, infections, other autoimmune diseases, or malignancies. Here, we report an 42-year-old female presented to us with diarrhea, nausea-vomiting, fever, chills and jaundice for two days. Hematological investigations revealed hemolytic anemia. Direct Coombs test was positive. The patient was diagnosed acute tubuler necrosis with autoimmune hemolytic anemia. Methylprednisolone 40 mg/day was started considering autoimmune hemolytic anemia. She was on hemodialysis at regular intervals. After 4 weeks, the patient was symptomatically improved with remission of acute tubuler necrosis and hemolytic anemia. In our case, the association of AIHA due to acute gastroenteritis and acute tubular insufficiency was considered suitable for the presentation because of its rare occurrence. |
| first_indexed | 2024-04-10T12:53:25Z |
| format | Article |
| id | doaj.art-0a8a8193e6614f3a82434cf842ed11b7 |
| institution | Directory Open Access Journal |
| issn | 2687-4245 |
| language | English |
| last_indexed | 2024-04-10T12:53:25Z |
| publishDate | 2021-03-01 |
| publisher | Nizameddin KOCA |
| record_format | Article |
| series | Turkish Journal of Internal Medicine |
| spelling | doaj.art-0a8a8193e6614f3a82434cf842ed11b72023-02-15T16:13:37ZengNizameddin KOCATurkish Journal of Internal Medicine2687-42452021-03-013Supplement 112012210.46310/tjim.8770281881Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute GastroenteritisMehmet Sezen0Abdülmecit Yıldız1Mahmut Yavuz2Kamil Dilek3Mustafa Güllülü4Ayşegül Oruç5Mehmet Fethullah Aydın6Alparslan Ersoy7BURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİBURSA ULUDAĞ ÜNİVERSİTESİAbstract Autoimmune hemolytic anemia (AIHA) is a rare disease with a rate of 1-3 in 100,000 in adults. AIHA are defined as primary (idiopathic) or secondary depending on the presence or absence of accompanying disease. Secondary causes include drugs, immunodeficiencies, infections, other autoimmune diseases, or malignancies. Here, we report an 42-year-old female presented to us with diarrhea, nausea-vomiting, fever, chills and jaundice for two days. Hematological investigations revealed hemolytic anemia. Direct Coombs test was positive. The patient was diagnosed acute tubuler necrosis with autoimmune hemolytic anemia. Methylprednisolone 40 mg/day was started considering autoimmune hemolytic anemia. She was on hemodialysis at regular intervals. After 4 weeks, the patient was symptomatically improved with remission of acute tubuler necrosis and hemolytic anemia. In our case, the association of AIHA due to acute gastroenteritis and acute tubular insufficiency was considered suitable for the presentation because of its rare occurrence.https://dergipark.org.tr/tr/download/article-file/1565392acute tubular necrosisautoimmune hemolytic anemiaacute gastroenteritis |
| spellingShingle | Mehmet Sezen Abdülmecit Yıldız Mahmut Yavuz Kamil Dilek Mustafa Güllülü Ayşegül Oruç Mehmet Fethullah Aydın Alparslan Ersoy Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis Turkish Journal of Internal Medicine acute tubular necrosis autoimmune hemolytic anemia acute gastroenteritis |
| title | Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis |
| title_full | Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis |
| title_fullStr | Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis |
| title_full_unstemmed | Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis |
| title_short | Acute Tubular Necrosis Associated with Autoimmune Hemolytic Anemia due to Acute Gastroenteritis |
| title_sort | acute tubular necrosis associated with autoimmune hemolytic anemia due to acute gastroenteritis |
| topic | acute tubular necrosis autoimmune hemolytic anemia acute gastroenteritis |
| url | https://dergipark.org.tr/tr/download/article-file/1565392 |
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