The wasp venom antimicrobial peptide polybia‐CP and its synthetic derivatives display antiplasmodial and anticancer properties

The wasp venom antimicrobial peptide polybia‐CP and its synthetic derivatives display antiplasmodial and anticancer properties

Abstract The wasp venom‐derived antimicrobial peptide polybia‐CP has been previously shown to exhibit potent antimicrobial activity, but it is also highly toxic. Previously, using a physicochemical‐guided peptide design strategy, we reversed its toxicity while preserving and even enhancing its antib...

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Bibliographic Details
Main Authors: Marcelo D. T. Torres, Adriana F. Silva, Gislaine P. Andrade, Cibele N. Pedron, Giselle Cerchiaro, Anderson O. Ribeiro, Vani X. Oliveira Jr, Cesar de laFuente‐Nunez
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Bioengineering & Translational Medicine
Subjects:
antimicrobial peptides
Polybia‐CP
rational design
structure‐guided design
wasp venom peptide
Online Access:https://doi.org/10.1002/btm2.10167

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