Human forebrain organoids reveal connections between valproic acid exposure and autism risk

Human forebrain organoids reveal connections between valproic acid exposure and autism risk

Abstract Valproic acid (VPA) exposure as an environmental factor that confers risk of autism spectrum disorder (ASD), its functional mechanisms in the human brain remain unclear since relevant studies are currently restricted to two-dimensional cell cultures and animal models. To identify mechanisms...

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Bibliographic Details
Main Authors: Qingtuan Meng, Wendiao Zhang, Xuan Wang, Chuan Jiao, Sheng Xu, Chunyu Liu, Beisha Tang, Chao Chen
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01898-x

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