Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes?
The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared b...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2014-10-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/431 |
| _version_ | 1818026119943684096 |
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| author | Seyed Alireza Mahdaviani Seyed Amir Mohajerani Mohammad Fakhri Mazaher Ebrahimi Bahram Bashardoost Seyed Jafar Razavi Masoumeh Toolabi Ali Tajik Soheila Khalilzadeh Mohamad Reza Masjedi |
| author_facet | Seyed Alireza Mahdaviani Seyed Amir Mohajerani Mohammad Fakhri Mazaher Ebrahimi Bahram Bashardoost Seyed Jafar Razavi Masoumeh Toolabi Ali Tajik Soheila Khalilzadeh Mohamad Reza Masjedi |
| author_sort | Seyed Alireza Mahdaviani |
| collection | DOAJ |
| description | The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared between two groups. There was no significant differences between variables like sex, age of onset (p=0.75), severity (p=0.70), and family history among the two groups (p=0.42). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 ± 3.19 and 9.75 ± 2.35 years, respectively, p=0.02). The controversy lingers over the presence of a completely distinct phenotype of non-atopic asthma in children. Our study suggested that phenotypes of allergic and non-allergic asthma in children were not entirely distinct. |
| first_indexed | 2024-12-10T04:26:57Z |
| format | Article |
| id | doaj.art-0a8da889a2c741d59232ae4cf0a7a281 |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-12-10T04:26:57Z |
| publishDate | 2014-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-0a8da889a2c741d59232ae4cf0a7a2812022-12-22T02:02:16ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492014-10-01135396Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes?Seyed Alireza Mahdaviani0Seyed Amir Mohajerani1Mohammad Fakhri2Mazaher Ebrahimi3Bahram Bashardoost4Seyed Jafar Razavi5Masoumeh Toolabi6Ali Tajik7Soheila Khalilzadeh8Mohamad Reza Masjedi9Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Telemedicine Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Community medicine department, Tehran University of Medical Science, Tehran, Iran.Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.Telemedicine Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared between two groups. There was no significant differences between variables like sex, age of onset (p=0.75), severity (p=0.70), and family history among the two groups (p=0.42). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 ± 3.19 and 9.75 ± 2.35 years, respectively, p=0.02). The controversy lingers over the presence of a completely distinct phenotype of non-atopic asthma in children. Our study suggested that phenotypes of allergic and non-allergic asthma in children were not entirely distinct.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/431AllergicAsthmaChildrenNon allergicPhenotype |
| spellingShingle | Seyed Alireza Mahdaviani Seyed Amir Mohajerani Mohammad Fakhri Mazaher Ebrahimi Bahram Bashardoost Seyed Jafar Razavi Masoumeh Toolabi Ali Tajik Soheila Khalilzadeh Mohamad Reza Masjedi Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? Iranian Journal of Allergy, Asthma and Immunology Allergic Asthma Children Non allergic Phenotype |
| title | Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? |
| title_full | Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? |
| title_fullStr | Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? |
| title_full_unstemmed | Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? |
| title_short | Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes? |
| title_sort | allergic and nonallergic asthma in children are they distinct phenotypes |
| topic | Allergic Asthma Children Non allergic Phenotype |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/431 |
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