SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis

SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis

Abstract Endometrial regenerative cells (ERCs) are a new type of mesenchymal-like stromal cells, and their therapeutic potential has been tested in a variety of disease models. SDF-1/CXCR4 axis plays a chemotaxis role in stem/stromal cell migration. The aim of the present study was to investigate th...

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Bibliographic Details
Main Authors: Xiang Li, Xu Lan, Yiming Zhao, Grace Wang, Ganggang Shi, Hongyue Li, Yonghao Hu, Xiaoxi Xu, Baoren Zhang, Kui Ye, Xiangying Gu, Caigan Du, Hao Wang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Stem Cell Research & Therapy
Subjects:
Endometrial regenerative cells
Stromal cell-derived factor-1
C-X-C chemokine receptor type 4
Immunoregulation
Online Access:http://link.springer.com/article/10.1186/s13287-019-1298-6

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