Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjögren’s syndrome

Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjögren’s syndrome

Salivary and lacrimal gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by mononuclear cell infiltration, resulting in lacrimal and salivary gland impairment. We have previously shown distinct prevalence of adipose tissue replacem...

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Bibliographic Details
Main Authors: Kathrine Skarstein, Janicke Liaaen Jensen, Hilde Galtung, Roland Jonsson, Karl Brokstad, Lara A. Aqrawi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Autoimmunity
Subjects:
fatty infiltration
adipocytes
b cells
plasma cells
autoantigens
salivary glands
sjögren’s syndrome
autoimmunity
Online Access:http://dx.doi.org/10.1080/08916934.2019.1684475

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