Acetylated Thioredoxin Reductase 1 Resists Oxidative Inactivation

Acetylated Thioredoxin Reductase 1 Resists Oxidative Inactivation

Thioredoxin Reductase 1 (TrxR1) is an enzyme that protects human cells against reactive oxygen species generated during oxidative stress or in response to chemotherapies. Acetylation of TrxR1 is associated with oxidative stress, but the function of TrxR1 acetylation in oxidizing conditions is unknow...

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Bibliographic Details
Main Authors: David. E. Wright, Nikolaus Panaseiko, Patrick O’Donoghue
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Chemistry
Subjects:
acetylation
enzymology
genetic code expansion
oxidation
post-translational modification
redox biology
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.747236/full

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