Hyponatremic Cognitive Dysfunction Resulting from Drug-Drug-Gene Interaction between Sertraline and Cannabidiol in an Intermediate CYP2C19 Metabolizer Patient

Hyponatremic Cognitive Dysfunction Resulting from Drug-Drug-Gene Interaction between Sertraline and Cannabidiol in an Intermediate CYP2C19 Metabolizer Patient

Background: Pharmacogenomics (PGx) can provide more precision in determining causation of adverse drug reactions (ADRs) from drug-drug-gene interaction clinical application. Case Summary: Patient was an intermediate CYP2C19 metabolizer on stable therapy taking a low but therapeutic dose of sertra...

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Bibliographic Details
Main Authors: Jade Nanan, Sheena Crosby, Michael J. Schuh
Format: Article
Language:English
Published: University of Minnesota Libraries Publishing 2022-09-01
Series:INNOVATIONS in Pharmacy
Subjects:
CYP2C19, Hyponatremia, Drug-drug-gene interaction, pharmacogenomics, cannabidiol, PGx
Online Access:https://pubs.lib.umn.edu/index.php/innovations/article/view/4890

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