Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma
Abstract Background Transoral salvage surgery has the potential to preserve a patient's quality of life. Therefore, we investigated the outcomes, safety, and risk factors for postoperative complications of salvage transoral videolaryngoscopic surgery (TOVS) for recurrent hypopharyngeal carcinom...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-06-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.1068 |
| _version_ | 1827921724938649600 |
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| author | Akihiro Sakai Koji Ebisumoto Hiroaki Iijima Mayu Yamauchi Takanobu Teramura Aritomo Yamazaki Takane Watanabe Toshihide Inagi Daisuke Maki Kenji Okami |
| author_facet | Akihiro Sakai Koji Ebisumoto Hiroaki Iijima Mayu Yamauchi Takanobu Teramura Aritomo Yamazaki Takane Watanabe Toshihide Inagi Daisuke Maki Kenji Okami |
| author_sort | Akihiro Sakai |
| collection | DOAJ |
| description | Abstract Background Transoral salvage surgery has the potential to preserve a patient's quality of life. Therefore, we investigated the outcomes, safety, and risk factors for postoperative complications of salvage transoral videolaryngoscopic surgery (TOVS) for recurrent hypopharyngeal carcinoma after radiotherapy (RT) or chemoradiotherapy (CRT). Methods This retrospective analysis enrolled patients with hypopharyngeal cancer who had a history of RT or CRT and underwent TOVS from January 2008 to June 2021. The factors related to postoperative complications, postoperative swallowing functions and survival rates were analyzed. Results Seven patients (36.8%) of the 19 patients developed complications. Severe dysphagia was the primary complication, and post‐cricoid resection was a complication risk factor. The FOSS score was significantly lower in the salvage treatment group. The survival rates were: 3‐year overall survival: 94.4%; disease‐specific survival: 94.4%; 5‐year overall survival: 62.3%; and disease‐specific survival: 86.6%. Conclusions Salvage TOVS for hypopharyngeal cancer was feasible, and oncologically and functionally reasonable. Level of Evidence: 2b. |
| first_indexed | 2024-03-13T04:31:35Z |
| format | Article |
| id | doaj.art-0a972d5c068a45008f197accff2b520a |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-03-13T04:31:35Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-0a972d5c068a45008f197accff2b520a2023-06-19T10:16:46ZengWileyLaryngoscope Investigative Otolaryngology2378-80382023-06-018366767410.1002/lio2.1068Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinomaAkihiro Sakai0Koji Ebisumoto1Hiroaki Iijima2Mayu Yamauchi3Takanobu Teramura4Aritomo Yamazaki5Takane Watanabe6Toshihide Inagi7Daisuke Maki8Kenji Okami9Department of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanDepartment of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara JapanAbstract Background Transoral salvage surgery has the potential to preserve a patient's quality of life. Therefore, we investigated the outcomes, safety, and risk factors for postoperative complications of salvage transoral videolaryngoscopic surgery (TOVS) for recurrent hypopharyngeal carcinoma after radiotherapy (RT) or chemoradiotherapy (CRT). Methods This retrospective analysis enrolled patients with hypopharyngeal cancer who had a history of RT or CRT and underwent TOVS from January 2008 to June 2021. The factors related to postoperative complications, postoperative swallowing functions and survival rates were analyzed. Results Seven patients (36.8%) of the 19 patients developed complications. Severe dysphagia was the primary complication, and post‐cricoid resection was a complication risk factor. The FOSS score was significantly lower in the salvage treatment group. The survival rates were: 3‐year overall survival: 94.4%; disease‐specific survival: 94.4%; 5‐year overall survival: 62.3%; and disease‐specific survival: 86.6%. Conclusions Salvage TOVS for hypopharyngeal cancer was feasible, and oncologically and functionally reasonable. Level of Evidence: 2b.https://doi.org/10.1002/lio2.1068hypopharyngeal carcinomaradiotherapyrecurrencesalvage surgerytransoral videolaryngoscopic surgery |
| spellingShingle | Akihiro Sakai Koji Ebisumoto Hiroaki Iijima Mayu Yamauchi Takanobu Teramura Aritomo Yamazaki Takane Watanabe Toshihide Inagi Daisuke Maki Kenji Okami Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma Laryngoscope Investigative Otolaryngology hypopharyngeal carcinoma radiotherapy recurrence salvage surgery transoral videolaryngoscopic surgery |
| title | Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma |
| title_full | Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma |
| title_fullStr | Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma |
| title_full_unstemmed | Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma |
| title_short | Salvage transoral videolaryngoscopic surgery for post‐irradiation recurrence of hypopharyngeal carcinoma |
| title_sort | salvage transoral videolaryngoscopic surgery for post irradiation recurrence of hypopharyngeal carcinoma |
| topic | hypopharyngeal carcinoma radiotherapy recurrence salvage surgery transoral videolaryngoscopic surgery |
| url | https://doi.org/10.1002/lio2.1068 |
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