Alpinumisoflavone ameliorates choroidal neovascularisation and fibrosis in age-related macular degeneration in in vitro and in vivo models

Alpinumisoflavone ameliorates choroidal neovascularisation and fibrosis in age-related macular degeneration in in vitro and in vivo models

Abstract Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly population. Anti-vascular endothelial growth factor (VEGF) antibody therapy is applicable to neovascularisation of AMD; however, the prevention of fibrosis after anti-VEGF monotherapy is an unmet medical n...

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Bibliographic Details
Main Authors:	Eunhye Yu, Yunjeong Song, Sun Mi Gu, Yang Hee Jo, Sang Won Yeon, Kyu Jin Han, Mi Kyeong Lee, Jung Kee Min, Jaesuk Yun
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-18531-y

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