Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases

Primary hyperparathyroidism is a common condition that affects 0.3% of the general population in which excessive production of PTH is there. With changing trends it is diagnosed early and asymptomatically with the improvements in routine biochemical tests and radiological procedures. The late bony c...

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Main Authors: Ruchi Bindal, Ajay Kumar, Harkanwal Preet Singh, Sanjiv Kumar Bansal, Aadya Sharma
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2013-07-01
Series:Journal of Laboratory Physicians
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/0974-2727.119863
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author Ruchi Bindal
Ajay Kumar
Harkanwal Preet Singh
Sanjiv Kumar Bansal
Aadya Sharma
author_facet Ruchi Bindal
Ajay Kumar
Harkanwal Preet Singh
Sanjiv Kumar Bansal
Aadya Sharma
author_sort Ruchi Bindal
collection DOAJ
description Primary hyperparathyroidism is a common condition that affects 0.3% of the general population in which excessive production of PTH is there. With changing trends it is diagnosed early and asymptomatically with the improvements in routine biochemical tests and radiological procedures. The late bony complications of the disease have therefore started to decline rapidly. The mandible is the predominantly affected site in the maxillofacial area. Maxillary involvement is rare. Here, we reported series of three cases of 30-40-year-old women with osteolytic lesions and bone resorption in maxilla or mandible. Two of presented cases demonstrated evidence of lesions in both mandible and maxilla which is a very rare event. A thorough diagnostic work-up emphasizing on biochemical and radiographic investigations were discussed. We highlighted the role of endocrinologist, oral and maxillofacial surgeons, general practitioner dentists, and radiologists in diagnosing and managing such patients.
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spelling doaj.art-0a98bedaf6b04ba1b7c1325b59cb5bcd2022-12-22T00:44:43ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262013-07-0150211311710.4103/0974-2727.119863Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual CasesRuchi Bindal0Ajay Kumar1Harkanwal Preet Singh2Sanjiv Kumar Bansal3Aadya Sharma4Departments of Oral Medicine and Radiology, Gurgaon, Haryana, IndiaDepartments of Oral and Maxillofacial Pathology and Microbiology, Yamuna Institute of Dental Sciences and Research, Yamunanagar, Gurgaon, Haryana, IndiaDepartments of Oral and Maxillofacial Pathology and Microbiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, IndiaDepartment of Biochemistry, SGT Medical College, Hospital and Research Institute, Budhera, IndiaDepartments of Oral and Maxillofacial Surgery, SGT Dental College, Gurgaon, Haryana, IndiaPrimary hyperparathyroidism is a common condition that affects 0.3% of the general population in which excessive production of PTH is there. With changing trends it is diagnosed early and asymptomatically with the improvements in routine biochemical tests and radiological procedures. The late bony complications of the disease have therefore started to decline rapidly. The mandible is the predominantly affected site in the maxillofacial area. Maxillary involvement is rare. Here, we reported series of three cases of 30-40-year-old women with osteolytic lesions and bone resorption in maxilla or mandible. Two of presented cases demonstrated evidence of lesions in both mandible and maxilla which is a very rare event. A thorough diagnostic work-up emphasizing on biochemical and radiographic investigations were discussed. We highlighted the role of endocrinologist, oral and maxillofacial surgeons, general practitioner dentists, and radiologists in diagnosing and managing such patients.http://www.thieme-connect.de/DOI/DOI?10.4103/0974-2727.119863endocrinologisthyperparathyroidismmandibleosteolytic lesions
spellingShingle Ruchi Bindal
Ajay Kumar
Harkanwal Preet Singh
Sanjiv Kumar Bansal
Aadya Sharma
Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
Journal of Laboratory Physicians
endocrinologist
hyperparathyroidism
mandible
osteolytic lesions
title Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
title_full Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
title_fullStr Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
title_full_unstemmed Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
title_short Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases
title_sort evidence based solving approach in diagnosis of primary hyperparathyroidism with oral manifestations report of three unusual cases
topic endocrinologist
hyperparathyroidism
mandible
osteolytic lesions
url http://www.thieme-connect.de/DOI/DOI?10.4103/0974-2727.119863
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AT harkanwalpreetsingh evidencebasedsolvingapproachindiagnosisofprimaryhyperparathyroidismwithoralmanifestationsreportofthreeunusualcases
AT sanjivkumarbansal evidencebasedsolvingapproachindiagnosisofprimaryhyperparathyroidismwithoralmanifestationsreportofthreeunusualcases
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