Targeting AKT Kinase in Hydroxytamoxifen-Resistant Breast Cancer Cells

Targeting AKT Kinase in Hydroxytamoxifen-Resistant Breast Cancer Cells

More than 650,000 people die each year from breast cancer, making it a particularly significant disease worldwide. The development of about 70% of breast tumors depends on steroid hormones, namely, estrogens. Estrogens trigger signaling pathways that support tumor growth and progression. Hydroxytamo...

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Bibliographic Details
Main Authors: Alexander M. Scherbakov, Fedor B. Bogdanov, Alexandra L. Mikhaylova, Olga E. Andreeva, Diana I. Salnikova
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Medical Sciences Forum
Subjects:
breast cancer
AKT inhibitor
10-DEBC
hydroxytamoxifen
luminespib
resistance
Online Access:https://www.mdpi.com/2673-9992/20/1/4

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