Amorphigenin from <i>Amorpha fruticosa</i> L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner

Amorphigenin from <i>Amorpha fruticosa</i> L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner

In this study, we investigated the depigmentation effect of <i>Amorpha fruticosa</i> L. root extract (RE), an herbal medicine. <i>A. fruticosa</i> RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations. Further, the RE decreased t...

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Bibliographic Details
Main Authors: Ki Won Lee, Dang Thi Nguyen, Minju Kim, Si Hyeon Lee, Seyeon Lim, Jisu Kim, Ki Hun Park, Jeong Yoon Kim, Jiyun Yoo, Cheol Hwangbo, Kwang Dong Kim
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Current Issues in Molecular Biology
Subjects:
<i>Amorpha fruticosa</i> L.
depigmentation
autophagy
amorphigenin
AMPK
Online Access:https://www.mdpi.com/1467-3045/44/7/196

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