Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives
Intracerebral hemorrhage (ICH) manifests precipitously and profoundly impairs the neurological function in patients who are affected. The etiology of subsequent injury post-ICH is multifaceted, characterized by the intricate interplay of various factors, rendering therapeutic interventions challengi...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-02-01
|
| Series: | Frontiers in Molecular Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2024.1327472/full |
| _version_ | 1797311623516389376 |
|---|---|
| author | Hao Dong Xin Wen Bai-Wen Zhang Zhe Wu Wei Zou |
| author_facet | Hao Dong Xin Wen Bai-Wen Zhang Zhe Wu Wei Zou |
| author_sort | Hao Dong |
| collection | DOAJ |
| description | Intracerebral hemorrhage (ICH) manifests precipitously and profoundly impairs the neurological function in patients who are affected. The etiology of subsequent injury post-ICH is multifaceted, characterized by the intricate interplay of various factors, rendering therapeutic interventions challenging. Astrocytes, a distinct class of glial cells, interact with neurons and microglia, and are implicated in a series of pathophysiological alterations following ICH. A comprehensive examination of the functions and mechanisms associated with astrocytic proteins may shed light on the role of astrocytes in ICH pathology and proffer innovative therapeutic avenues for ICH management. |
| first_indexed | 2024-03-08T02:02:24Z |
| format | Article |
| id | doaj.art-0aa274c5d81e4ada9d9dab3c5f3b9041 |
| institution | Directory Open Access Journal |
| issn | 1662-5099 |
| language | English |
| last_indexed | 2024-03-08T02:02:24Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Molecular Neuroscience |
| spelling | doaj.art-0aa274c5d81e4ada9d9dab3c5f3b90412024-02-14T04:17:44ZengFrontiers Media S.A.Frontiers in Molecular Neuroscience1662-50992024-02-011710.3389/fnmol.2024.13274721327472Astrocytes in intracerebral hemorrhage: impact and therapeutic objectivesHao Dong0Xin Wen1Bai-Wen Zhang2Zhe Wu3Wei Zou4The First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, ChinaThe First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, ChinaThe First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, ChinaThe First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, ChinaThe Third Department of Acupuncture and Moxibustion, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, ChinaIntracerebral hemorrhage (ICH) manifests precipitously and profoundly impairs the neurological function in patients who are affected. The etiology of subsequent injury post-ICH is multifaceted, characterized by the intricate interplay of various factors, rendering therapeutic interventions challenging. Astrocytes, a distinct class of glial cells, interact with neurons and microglia, and are implicated in a series of pathophysiological alterations following ICH. A comprehensive examination of the functions and mechanisms associated with astrocytic proteins may shed light on the role of astrocytes in ICH pathology and proffer innovative therapeutic avenues for ICH management.https://www.frontiersin.org/articles/10.3389/fnmol.2024.1327472/fullastrocytescrosstalkinflammatory responseintracerebral hemorrhageneurological function |
| spellingShingle | Hao Dong Xin Wen Bai-Wen Zhang Zhe Wu Wei Zou Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives Frontiers in Molecular Neuroscience astrocytes crosstalk inflammatory response intracerebral hemorrhage neurological function |
| title | Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives |
| title_full | Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives |
| title_fullStr | Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives |
| title_full_unstemmed | Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives |
| title_short | Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives |
| title_sort | astrocytes in intracerebral hemorrhage impact and therapeutic objectives |
| topic | astrocytes crosstalk inflammatory response intracerebral hemorrhage neurological function |
| url | https://www.frontiersin.org/articles/10.3389/fnmol.2024.1327472/full |
| work_keys_str_mv | AT haodong astrocytesinintracerebralhemorrhageimpactandtherapeuticobjectives AT xinwen astrocytesinintracerebralhemorrhageimpactandtherapeuticobjectives AT baiwenzhang astrocytesinintracerebralhemorrhageimpactandtherapeuticobjectives AT zhewu astrocytesinintracerebralhemorrhageimpactandtherapeuticobjectives AT weizou astrocytesinintracerebralhemorrhageimpactandtherapeuticobjectives |