Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases
Since the first case has emerged, different neurological complications associated with Coronavirus disease-2019 (COVID-19) have been reported all over the world. The association between coronavirus and Guillain-Barré syndrome (GBS) has also been reported before. Unfortunately, there is no certain me...
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2022-03-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjn&un=TJN-86094 |
| _version_ | 1797921737919168512 |
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| author | Zeynep Ünlütürk Çağatay Hilmi Öncel Barış Haytı Çağdaş Erdoğan |
| author_facet | Zeynep Ünlütürk Çağatay Hilmi Öncel Barış Haytı Çağdaş Erdoğan |
| author_sort | Zeynep Ünlütürk |
| collection | DOAJ |
| description | Since the first case has emerged, different neurological complications associated with Coronavirus disease-2019 (COVID-19) have been reported all over the world. The association between coronavirus and Guillain-Barré syndrome (GBS) has also been reported before. Unfortunately, there is no certain mechanism about this association yet. Molecular mimicry is one of the first hypotheses to express the undesirable autoimmunity in GBS. According to this; the antibodies produced against virus may target peripheral nerves or spinal nerve roots. The entity of direct viral neurotoxicity has also been discussed. Here, we presented four variants of GBS associated with coronavirus that we followed up in our clinic between September-December 2020. While the first patient had demyelinating sensorimotor neuropathy concurrent with COVID-19, the other ones were postinfectious. The second patient had motor axonal neuropathy and the third one had sensorimotor axonal neuropathy. There was Miller-Fisher syndrome and GBS overlap in the fourth patient. |
| first_indexed | 2024-04-10T14:20:20Z |
| format | Article |
| id | doaj.art-0aa6e445a8ba41a99145a2a1b778e15b |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T14:20:20Z |
| publishDate | 2022-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-0aa6e445a8ba41a99145a2a1b778e15b2023-02-15T16:09:19ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452022-03-01281515410.4274/tnd.2021.86094TJN-86094Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical CasesZeynep Ünlütürk0Çağatay Hilmi Öncel1Barış Haytı2Çağdaş Erdoğan3Pamukkale University Faculty of Medicine, Department of Neurology, Denizli, TurkeyPamukkale University Faculty of Medicine, Department of Neurology, Denizli, TurkeyPamukkale University Faculty of Medicine, Department of Neurology, Denizli, TurkeyPamukkale University Faculty of Medicine, Department of Neurology, Denizli, TurkeySince the first case has emerged, different neurological complications associated with Coronavirus disease-2019 (COVID-19) have been reported all over the world. The association between coronavirus and Guillain-Barré syndrome (GBS) has also been reported before. Unfortunately, there is no certain mechanism about this association yet. Molecular mimicry is one of the first hypotheses to express the undesirable autoimmunity in GBS. According to this; the antibodies produced against virus may target peripheral nerves or spinal nerve roots. The entity of direct viral neurotoxicity has also been discussed. Here, we presented four variants of GBS associated with coronavirus that we followed up in our clinic between September-December 2020. While the first patient had demyelinating sensorimotor neuropathy concurrent with COVID-19, the other ones were postinfectious. The second patient had motor axonal neuropathy and the third one had sensorimotor axonal neuropathy. There was Miller-Fisher syndrome and GBS overlap in the fourth patient.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjn&un=TJN-86094covid-19guillain-barré syndromemfs-gbs overlap |
| spellingShingle | Zeynep Ünlütürk Çağatay Hilmi Öncel Barış Haytı Çağdaş Erdoğan Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases Türk Nöroloji Dergisi covid-19 guillain-barré syndrome mfs-gbs overlap |
| title | Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases |
| title_full | Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases |
| title_fullStr | Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases |
| title_full_unstemmed | Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases |
| title_short | Different Guillain-Barré Syndrome Variants Associated with COVID-19: Report of 4 Clinical Cases |
| title_sort | different guillain barre syndrome variants associated with covid 19 report of 4 clinical cases |
| topic | covid-19 guillain-barré syndrome mfs-gbs overlap |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjn&un=TJN-86094 |
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