Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2
While mucocutaneous manifestations of COVID-19 have been frequently reported and added to our knowledge every day during the pandemic, another issue is the COVID-related diseases that can present as intensified lesions of underlying diseases, a new disease, or changes in the behavior of an old lesio...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-10-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.728411/full |
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| author | Zahra Lotfi Zahra Lotfi Anousheh Haghighi Amirhossein Akbarzadehpasha Samaneh Mozafarpoor Azadeh Goodarzi |
| author_facet | Zahra Lotfi Zahra Lotfi Anousheh Haghighi Amirhossein Akbarzadehpasha Samaneh Mozafarpoor Azadeh Goodarzi |
| author_sort | Zahra Lotfi |
| collection | DOAJ |
| description | While mucocutaneous manifestations of COVID-19 have been frequently reported and added to our knowledge every day during the pandemic, another issue is the COVID-related diseases that can present as intensified lesions of underlying diseases, a new disease, or changes in the behavior of an old lesion. Given that immune system overreaction and cytokine storm are among the most prominent events in COVID-19, the incidence of autoimmune diseases is expected to increase after COVID-19, as confirmed in several reports. To increase the body of knowledge about short- and long-term outcomes of COVID-19 for specialists, it is essential that similar cases be reported and collected for years to come. The present study investigated a case of pansclerotic morphea that rapidly progressed a few weeks after infection with COVID-19 in a 57-year-old woman with no history of any autoimmune skin or rheumatic diseases. She was prescribed outpatient COVID-19 treatment of azithromycin, vitamins D and C, and then quarantined for 2 weeks. The manifestations of the disease were exacerbated at each follow-up and sampling visit at short intervals. This kind of pansclerotic morphea is reported for the first time. |
| first_indexed | 2024-12-18T02:12:46Z |
| format | Article |
| id | doaj.art-0aaa2be9997948bea6db89f9aee906a4 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-18T02:12:46Z |
| publishDate | 2021-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-0aaa2be9997948bea6db89f9aee906a42022-12-21T21:24:27ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-10-01810.3389/fmed.2021.728411728411Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2Zahra Lotfi0Zahra Lotfi1Anousheh Haghighi2Amirhossein Akbarzadehpasha3Samaneh Mozafarpoor4Azadeh Goodarzi5Department of Dermatology, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, IranDepartment of Rheumatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, IranDepartment of Internal Medicine, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, IranDepartment of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, IranWhile mucocutaneous manifestations of COVID-19 have been frequently reported and added to our knowledge every day during the pandemic, another issue is the COVID-related diseases that can present as intensified lesions of underlying diseases, a new disease, or changes in the behavior of an old lesion. Given that immune system overreaction and cytokine storm are among the most prominent events in COVID-19, the incidence of autoimmune diseases is expected to increase after COVID-19, as confirmed in several reports. To increase the body of knowledge about short- and long-term outcomes of COVID-19 for specialists, it is essential that similar cases be reported and collected for years to come. The present study investigated a case of pansclerotic morphea that rapidly progressed a few weeks after infection with COVID-19 in a 57-year-old woman with no history of any autoimmune skin or rheumatic diseases. She was prescribed outpatient COVID-19 treatment of azithromycin, vitamins D and C, and then quarantined for 2 weeks. The manifestations of the disease were exacerbated at each follow-up and sampling visit at short intervals. This kind of pansclerotic morphea is reported for the first time.https://www.frontiersin.org/articles/10.3389/fmed.2021.728411/fullskin disordermorpheageneralized morpheadermatologypansclerotic morphea |
| spellingShingle | Zahra Lotfi Zahra Lotfi Anousheh Haghighi Amirhossein Akbarzadehpasha Samaneh Mozafarpoor Azadeh Goodarzi Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 Frontiers in Medicine skin disorder morphea generalized morphea dermatology pansclerotic morphea |
| title | Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 |
| title_full | Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 |
| title_fullStr | Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 |
| title_full_unstemmed | Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 |
| title_short | Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2 |
| title_sort | pansclerotic morphea following covid 19 a case report and review of literature on rheumatologic and non rheumatologic dermatologic immune mediated disorders induced by sars cov 2 |
| topic | skin disorder morphea generalized morphea dermatology pansclerotic morphea |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2021.728411/full |
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