Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study
Abstract Background Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. Methods Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns inc...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12916-022-02557-0 |
| _version_ | 1811250025584394240 |
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| author | Yunqing Zhu Junning Fan Jun Lv Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Feifei Li Xiaoming Yang Daniel Avery Junshi Chen Zhengming Chen Canqing Yu Liming Li on behalf of the China Kadoorie Biobank Collaborative Group |
| author_facet | Yunqing Zhu Junning Fan Jun Lv Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Feifei Li Xiaoming Yang Daniel Avery Junshi Chen Zhengming Chen Canqing Yu Liming Li on behalf of the China Kadoorie Biobank Collaborative Group |
| author_sort | Yunqing Zhu |
| collection | DOAJ |
| description | Abstract Background Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. Methods Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions. Results During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89–0.96), 0.76 (0.74–0.77), and 0.85 (0.82–0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00–1.18) and 1.42 (1.31–1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (P for trend < 0.001). Conclusions Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults. |
| first_indexed | 2024-04-12T15:57:52Z |
| format | Article |
| id | doaj.art-0aabf029160542d7a816f6504c7732fe |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-04-12T15:57:52Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-0aabf029160542d7a816f6504c7732fe2022-12-22T03:26:18ZengBMCBMC Medicine1741-70152022-10-012011910.1186/s12916-022-02557-0Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese studyYunqing Zhu0Junning Fan1Jun Lv2Yu Guo3Pei Pei4Ling Yang5Yiping Chen6Huaidong Du7Feifei Li8Xiaoming Yang9Daniel Avery10Junshi Chen11Zhengming Chen12Canqing Yu13Liming Li14on behalf of the China Kadoorie Biobank Collaborative GroupDepartment of Epidemiology & Biostatistics, School of Public Health, Peking UniversityDepartment of Epidemiology & Biostatistics, School of Public Health, Peking UniversityDepartment of Epidemiology & Biostatistics, School of Public Health, Peking UniversityFuwai Hospital, Chinese Academy of Medical SciencesChinese Academy of Medical SciencesMedical Research Council Population Health Research Unit at the University of OxfordMedical Research Council Population Health Research Unit at the University of OxfordMedical Research Council Population Health Research Unit at the University of OxfordNCDs Prevention and Control Department, Qingdao CDCClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of OxfordClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of OxfordChina National Center for Food Safety Risk AssessmentClinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of OxfordDepartment of Epidemiology & Biostatistics, School of Public Health, Peking UniversityDepartment of Epidemiology & Biostatistics, School of Public Health, Peking UniversityAbstract Background Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. Methods Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions. Results During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89–0.96), 0.76 (0.74–0.77), and 0.85 (0.82–0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00–1.18) and 1.42 (1.31–1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (P for trend < 0.001). Conclusions Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults.https://doi.org/10.1186/s12916-022-02557-0Sleep patternsFrailtyProspective cohort study |
| spellingShingle | Yunqing Zhu Junning Fan Jun Lv Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Feifei Li Xiaoming Yang Daniel Avery Junshi Chen Zhengming Chen Canqing Yu Liming Li on behalf of the China Kadoorie Biobank Collaborative Group Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study BMC Medicine Sleep patterns Frailty Prospective cohort study |
| title | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_full | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_fullStr | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_full_unstemmed | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_short | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_sort | maintaining healthy sleep patterns and frailty transitions a prospective chinese study |
| topic | Sleep patterns Frailty Prospective cohort study |
| url | https://doi.org/10.1186/s12916-022-02557-0 |
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