Systemic Inflammation Associates With a Myeloid Inflamed Tumor Microenvironment in Primary Resected Colon Cancer—May Cold Tumors Simply Be Too Hot?

Systemic Inflammation Associates With a Myeloid Inflamed Tumor Microenvironment in Primary Resected Colon Cancer—May Cold Tumors Simply Be Too Hot?

Systemic inflammation measured by the acute-phase protein CRP associates with poor outcome across cancer types. In contrast, local tumor-associated inflammation, primarily evaluated by T-lymphocytes, correlates with favorable prognosis. Yet, little is known whether these two responses are related or...

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Bibliographic Details
Main Authors: Anne Helene Køstner, Patricia Switten Nielsen, Jeanette Baehr Georgsen, Erik Thorlund Parner, Mette Bak Nielsen, Christian Kersten, Torben Steiniche
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
systemic inflammation
C-reactive protein
multiplex
immunohistochemistry
colon cancer
myeloid inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.716342/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.716342/full

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