Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant

Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant

Immunization with thetumor-associated antigen GA733 glycoprotein, which is highly expressed in colorectal cancer, is considered to be a promising strategy for cancer prevention and treatment. We cloned a fusion gene of GA733 and immunoglobulin Fc fragment (GA733-Fc), and that of GA733-Fc and an endo...

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Bibliographic Details
Main Authors: Kibum Kim, Yang Joo Kang, Se Ra Park, Do-Sun Kim, Seung-Won Lee, Kinarm Ko, Daniel Ponndorf, Kisung Ko
Format: Article
Language:English
Published: PeerJ Inc. 2021-04-01
Series:PeerJ
Subjects:
Agroinfiltration
Fusion protein
KDEL
Molecular biopharming
Recombinant vaccine
Online Access:https://peerj.com/articles/10851.pdf

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