Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis

Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis

The nucleotide-binding oligomerization domain 2 (NOD2) is the key regulator of inflammatory responses and has been involved in the pathogenesis of rheumatoid arthritis (RA). Laboratory and in silico evaluations have demonstrated that some polymorphisms in 3ˊUTR of NOD2 gene could influence the secon...

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Bibliographic Details
Main Authors: Naeim Ehtesham, Behrang Alani, Deniz Mortazavi, Sara Azhdari, Taiebe Kenarangi, Emran Esmaeilzadeh, Bahram Pakzad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2021-04-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Inflammation
Polymorphism
Rheumatoid arthritis
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3094

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