The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period
Introduction: Oral local immune factors may play a protective role against oral diseases and defend against microbial agents. Salivary immunoglobulin A (IgA) is a major factor for the local host defence against caries and periodontal disease. The aims of this study were to determine the concentratio...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2007-01-01
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| Series: | Dental Research Journal |
| Subjects: | |
| Online Access: | http://journals.mui.ac.ir/drj/article/view/1544/623 |
| _version_ | 1818008185599950848 |
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| author | A. Jafarzadeh GH. Hassanshahi M. Kazemi-Arababadi A. Mostafaee M. Sadeghideh MA. Nematollahi |
| author_facet | A. Jafarzadeh GH. Hassanshahi M. Kazemi-Arababadi A. Mostafaee M. Sadeghideh MA. Nematollahi |
| author_sort | A. Jafarzadeh |
| collection | DOAJ |
| description | Introduction: Oral local immune factors may play a protective role against oral diseases and defend against microbial agents. Salivary immunoglobulin A (IgA) is a major factor for the local host defence against caries and periodontal disease. The aims of this study were to determine the concentrations of salivary IgA and IgE levels in breast-fed and formula-fed children in infancy period.Methods and Materials: Totally, 80 healthy 5 years old children were included in the study. According to type of feeding in infancy period, the children divided into two groups: 50 breast-fed and 30 formula-fed. One milliliter of saliva was collected from each participant, centrifuged, and stored at -70 )C. The salivary IgA and IgE concentrations were measured, using ELISA technique.Results: In breast-fed children, the salivary IgA level (39.6 mg/l ± 17.3) was significantly higher than that in formula-fed children (26.9 mg/l ± 14) (P=0.0001). However, the salivary IgE level was significantly lower in breast-fed children, comparing with formula fed ones (5.01 IU/ml ± 19.70 vs. 11.74 IU/ml ± 39.40) (P=0.047).Discussion: These results suggest that breast feeding enhances salivary IgA level in the early period of life which may contribute in oral cavity immunity. Higher salivary IgE level observed in formula-fed subjects may have a potential role in development of allergic or inflammatory reactions. |
| first_indexed | 2024-04-14T05:25:56Z |
| format | Article |
| id | doaj.art-0ab7bb3fea2545afbe8325c6e1bad405 |
| institution | Directory Open Access Journal |
| issn | 1735-3327 2008-0255 |
| language | English |
| last_indexed | 2024-04-14T05:25:56Z |
| publishDate | 2007-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dental Research Journal |
| spelling | doaj.art-0ab7bb3fea2545afbe8325c6e1bad4052022-12-22T02:09:58ZengWolters Kluwer Medknow PublicationsDental Research Journal1735-33272008-02552007-01-01411117The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy PeriodA. JafarzadehGH. HassanshahiM. Kazemi-ArababadiA. MostafaeeM. SadeghidehMA. NematollahiIntroduction: Oral local immune factors may play a protective role against oral diseases and defend against microbial agents. Salivary immunoglobulin A (IgA) is a major factor for the local host defence against caries and periodontal disease. The aims of this study were to determine the concentrations of salivary IgA and IgE levels in breast-fed and formula-fed children in infancy period.Methods and Materials: Totally, 80 healthy 5 years old children were included in the study. According to type of feeding in infancy period, the children divided into two groups: 50 breast-fed and 30 formula-fed. One milliliter of saliva was collected from each participant, centrifuged, and stored at -70 )C. The salivary IgA and IgE concentrations were measured, using ELISA technique.Results: In breast-fed children, the salivary IgA level (39.6 mg/l ± 17.3) was significantly higher than that in formula-fed children (26.9 mg/l ± 14) (P=0.0001). However, the salivary IgE level was significantly lower in breast-fed children, comparing with formula fed ones (5.01 IU/ml ± 19.70 vs. 11.74 IU/ml ± 39.40) (P=0.047).Discussion: These results suggest that breast feeding enhances salivary IgA level in the early period of life which may contribute in oral cavity immunity. Higher salivary IgE level observed in formula-fed subjects may have a potential role in development of allergic or inflammatory reactions.http://journals.mui.ac.ir/drj/article/view/1544/623Breast FeedingFormula FeedingSalivaIgAIgEChildren |
| spellingShingle | A. Jafarzadeh GH. Hassanshahi M. Kazemi-Arababadi A. Mostafaee M. Sadeghideh MA. Nematollahi The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period Dental Research Journal Breast Feeding Formula Feeding Saliva IgA IgE Children |
| title | The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period |
| title_full | The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period |
| title_fullStr | The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period |
| title_full_unstemmed | The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period |
| title_short | The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period |
| title_sort | comparison of salivary iga and ige levels in children with breast and formula feeding during infancy period |
| topic | Breast Feeding Formula Feeding Saliva IgA IgE Children |
| url | http://journals.mui.ac.ir/drj/article/view/1544/623 |
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