Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study

Unique aspects of New Zealand’s (NZ) health system allow for a novel pharmacoepidemiologic approach to conducting population-based clinical research. A defined cohort of surgical and trauma patients would facilitate future studies into opioid utilisation, outcomes, and other questions related to sur...

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Main Authors: Jiayi Gong, Amy Hai Yan Chan, Kebede Beyene, Alan Forbes Merry, Andrew Tomlin, Peter Jones
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmacoepidemiology
Subjects:
Online Access:https://www.mdpi.com/2813-0618/2/1/1
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author Jiayi Gong
Amy Hai Yan Chan
Kebede Beyene
Alan Forbes Merry
Andrew Tomlin
Peter Jones
author_facet Jiayi Gong
Amy Hai Yan Chan
Kebede Beyene
Alan Forbes Merry
Andrew Tomlin
Peter Jones
author_sort Jiayi Gong
collection DOAJ
description Unique aspects of New Zealand’s (NZ) health system allow for a novel pharmacoepidemiologic approach to conducting population-based clinical research. A defined cohort of surgical and trauma patients would facilitate future studies into opioid utilisation, outcomes, and other questions related to surgery and trauma. We aimed to describe all patients admitted to a NZ hospital with trauma or to undergo surgery between 1 January 2007 to 31 December 2019. This was a retrospective population-based study involving all hospital centres in NZ. We excluded patients with hospitalisation episodes for surgery or trauma one year before the event. We identified 1.78 million surgical only patients, 633,386 trauma only, and 250,800 trauma with surgery patients. Trauma only patients had the highest prevalence of death within one year of event (17.8%), history of opioid dispensing (18.3%), mental health disorders (17.0%) and chronic pain (2.3%). Moreover, trauma patients also had the highest prevalence of those with higher comorbidity burden. We plan to use this dataset for future research into the prevalence and outcomes of persistent opioid use, and to make our dataset available to other researchers upon request. Our findings of significant differences between cohorts suggest studies should treat surgical and trauma patients separately.
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spelling doaj.art-0ab8b2f229c64e4596e07fc701d9c5be2023-03-28T14:32:00ZengMDPI AGPharmacoepidemiology2813-06182022-12-012111210.3390/pharma2010001Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive StudyJiayi Gong0Amy Hai Yan Chan1Kebede Beyene2Alan Forbes Merry3Andrew Tomlin4Peter Jones5School of Pharmacy, Faculty of Medical & Health Sciences, The University of Auckland, Auckland 1023, New ZealandSchool of Pharmacy, Faculty of Medical & Health Sciences, The University of Auckland, Auckland 1023, New ZealandDepartment of Pharmaceutical and Administrative Sciences, University of Health Sciences and Pharmacy, St. Louis, MO 63110-1009, USADepartment of Anaesthesiology, School of Medicine, Faculty of Medical & Health Sciences, The University of Auckland, Auckland 1023, New ZealandSchool of Pharmacy, Faculty of Medical & Health Sciences, The University of Auckland, Auckland 1023, New ZealandDepartment of Surgery, School of Medicine, Faculty of Medical & Health Sciences, The University of Auckland, Auckland, 1023, New ZealandUnique aspects of New Zealand’s (NZ) health system allow for a novel pharmacoepidemiologic approach to conducting population-based clinical research. A defined cohort of surgical and trauma patients would facilitate future studies into opioid utilisation, outcomes, and other questions related to surgery and trauma. We aimed to describe all patients admitted to a NZ hospital with trauma or to undergo surgery between 1 January 2007 to 31 December 2019. This was a retrospective population-based study involving all hospital centres in NZ. We excluded patients with hospitalisation episodes for surgery or trauma one year before the event. We identified 1.78 million surgical only patients, 633,386 trauma only, and 250,800 trauma with surgery patients. Trauma only patients had the highest prevalence of death within one year of event (17.8%), history of opioid dispensing (18.3%), mental health disorders (17.0%) and chronic pain (2.3%). Moreover, trauma patients also had the highest prevalence of those with higher comorbidity burden. We plan to use this dataset for future research into the prevalence and outcomes of persistent opioid use, and to make our dataset available to other researchers upon request. Our findings of significant differences between cohorts suggest studies should treat surgical and trauma patients separately.https://www.mdpi.com/2813-0618/2/1/1surgerytraumapharmacoepidemiologyopioid
spellingShingle Jiayi Gong
Amy Hai Yan Chan
Kebede Beyene
Alan Forbes Merry
Andrew Tomlin
Peter Jones
Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
Pharmacoepidemiology
surgery
trauma
pharmacoepidemiology
opioid
title Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
title_full Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
title_fullStr Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
title_full_unstemmed Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
title_short Identifying Surgical and Trauma Patients in New Zealand for Opioid-Related Pharmacoepidemiological Research: A Descriptive Study
title_sort identifying surgical and trauma patients in new zealand for opioid related pharmacoepidemiological research a descriptive study
topic surgery
trauma
pharmacoepidemiology
opioid
url https://www.mdpi.com/2813-0618/2/1/1
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