An efficient synthesis of imidazo[2,1-b][1,3]thiazins via a one-pot, three-component and solvent-free reaction
A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in the presence of catalytic amount of p-toluene...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2016-10-01
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| Series: | Green Chemistry Letters and Reviews |
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| Online Access: | http://dx.doi.org/10.1080/17518253.2016.1231841 |
| Summary: | A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in the presence of catalytic amount of p-toluene sulfonic acid, in good and excellent yields. |
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| ISSN: | 1751-8253 1751-7192 |