In vitro study to evaluate the effect of granulocyte colony stimulating factor on colorectal adenocarcinoma and on mesenchymal stem cells trans differentiation into cancer stem cells by cancer cells derived exosomes

In vitro study to evaluate the effect of granulocyte colony stimulating factor on colorectal adenocarcinoma and on mesenchymal stem cells trans differentiation into cancer stem cells by cancer cells derived exosomes

Abstract Background Colorectal cancer (CRC) is a common and lethal malignancies with poor prognosis. CRC cells release extracellular vesicles called exosomes to facilitate tumor progression by passing bioactive molecules such as proteins and nucleic acids between cells of the tumor and their microen...

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Bibliographic Details
Main Authors: Azza Abusree Ahmed, Manar Monir, Dina Sabry, Abeer Mostafa
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
CRC
Exosomes
G-CSF
MALAT and CSCs
Online Access:https://doi.org/10.1186/s43088-023-00351-2

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