Emergence of the G118R Pan-Integrase Resistance Mutation as a Result of Low Compliance to a Dolutegravir-Based cART

Emergence of the G118R Pan-Integrase Resistance Mutation as a Result of Low Compliance to a Dolutegravir-Based cART

HIV-1 resistance towards integrase inhibitors is a potential threat of the success of HIV-1 combination treatment. G118R is a rare drug resistance mutation conferring pan-integrase resistance. Here, we describe the occurrence of G118R in a HIV-1 subtype-B-positive individual with major compliance pr...

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Bibliographic Details
Main Authors: Helene Mens, Lasse Fjordside, Jannik Fonager, Jan Gerstoft
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Infectious Disease Reports
Subjects:
HIV-1
integrase inhibitors
drug resistance
Online Access:https://www.mdpi.com/2036-7449/14/4/53

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