Pathogenic Pore Forming Proteins of <i>Plasmodium</i> Triggers the Necrosis of Endothelial Cells Attributed to Malaria Severity

Pathogenic Pore Forming Proteins of <i>Plasmodium</i> Triggers the Necrosis of Endothelial Cells Attributed to Malaria Severity

Severe malaria caused by <i>Plasmodium falciparum</i> poses a major global health problem with high morbidity and mortality. <i>P. falciparum</i> harbors a family of pore-forming proteins (PFPs), known as perforin like proteins (PLPs), which are structurally equivalent to pro...

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Bibliographic Details
Main Authors: Abhishek Shivappagowdar, Swati Garg, Akriti Srivastava, Rahul S. Hada, Inderjeet Kalia, Agam P. Singh, Lalit C. Garg, Soumya Pati, Shailja Singh
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Toxins
Subjects:
malaria
<i>Plasmodium falciparum</i>
perforin like proteins
necrosis
blebbing
calcium
Online Access:https://www.mdpi.com/2072-6651/13/1/62

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