Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed!
Partial thromboplastin time, kaolin (PTTK) is a global test sensitive to low levels of all the coagulation factors, except Factor VII and Factor XIII. Patients with extensive cancer have a propensity to develop a shortened PTTK. Our breast cancer patient had a prolonged PTTK result roughly 4 times t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | The Indian Anaesthetists' Forum |
| Subjects: | |
| Online Access: | http://www.theiaforum.org/article.asp?issn=0973-0311;year=2017;volume=18;issue=1;spage=23;epage=26;aulast=Shah |
| _version_ | 1828284502940581888 |
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| author | Shagun Bhatia Shah Vani Bhageria Binod Kumar Naithani Ajay Kumar Bhargava |
| author_facet | Shagun Bhatia Shah Vani Bhageria Binod Kumar Naithani Ajay Kumar Bhargava |
| author_sort | Shagun Bhatia Shah |
| collection | DOAJ |
| description | Partial thromboplastin time, kaolin (PTTK) is a global test sensitive to low levels of all the coagulation factors, except Factor VII and Factor XIII. Patients with extensive cancer have a propensity to develop a shortened PTTK. Our breast cancer patient had a prolonged PTTK result roughly 4 times the normal values. A detailed description of the preoperative workup including the special investigations is required to ascertain the cause of the prolongation and precautions taken, leading to successful breast cancer surgery and postoperative period in this patient follows. Allowing the surgeon to operate a patient with a PTTK >120 s and simultaneously at risk of thrombosis due to lupus anticoagulant is possible with a calculated risk and thorough preoperative evaluation. Prophylactic fresh frozen plasma and deep venous thrombosis prophylaxis have an important role. |
| first_indexed | 2024-04-13T09:02:54Z |
| format | Article |
| id | doaj.art-0abe66fb8b1042c0b5fbac1c3659a901 |
| institution | Directory Open Access Journal |
| issn | 0973-0311 0973-0311 |
| language | English |
| last_indexed | 2024-04-13T09:02:54Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Indian Anaesthetists' Forum |
| spelling | doaj.art-0abe66fb8b1042c0b5fbac1c3659a9012022-12-22T02:53:04ZengWolters Kluwer Medknow PublicationsThe Indian Anaesthetists' Forum0973-03110973-03112017-01-01181232610.4103/TheIAForum.TheIAForum_8_17Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed!Shagun Bhatia ShahVani BhageriaBinod Kumar NaithaniAjay Kumar BhargavaPartial thromboplastin time, kaolin (PTTK) is a global test sensitive to low levels of all the coagulation factors, except Factor VII and Factor XIII. Patients with extensive cancer have a propensity to develop a shortened PTTK. Our breast cancer patient had a prolonged PTTK result roughly 4 times the normal values. A detailed description of the preoperative workup including the special investigations is required to ascertain the cause of the prolongation and precautions taken, leading to successful breast cancer surgery and postoperative period in this patient follows. Allowing the surgeon to operate a patient with a PTTK >120 s and simultaneously at risk of thrombosis due to lupus anticoagulant is possible with a calculated risk and thorough preoperative evaluation. Prophylactic fresh frozen plasma and deep venous thrombosis prophylaxis have an important role.http://www.theiaforum.org/article.asp?issn=0973-0311;year=2017;volume=18;issue=1;spage=23;epage=26;aulast=ShahBreast cancer surgerydecreased Factor XIlupus anticoagulantraised partial thromboplastin time kaolinthromboelastography |
| spellingShingle | Shagun Bhatia Shah Vani Bhageria Binod Kumar Naithani Ajay Kumar Bhargava Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! The Indian Anaesthetists' Forum Breast cancer surgery decreased Factor XI lupus anticoagulant raised partial thromboplastin time kaolin thromboelastography |
| title | Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! |
| title_full | Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! |
| title_fullStr | Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! |
| title_full_unstemmed | Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! |
| title_short | Unbelievable but true: Partial thromboplastin time, kaolin 120 s and yet no surgical bleed! |
| title_sort | unbelievable but true partial thromboplastin time kaolin 120 s and yet no surgical bleed |
| topic | Breast cancer surgery decreased Factor XI lupus anticoagulant raised partial thromboplastin time kaolin thromboelastography |
| url | http://www.theiaforum.org/article.asp?issn=0973-0311;year=2017;volume=18;issue=1;spage=23;epage=26;aulast=Shah |
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